ADRM1, adhesion regulating molecule 1

ADRM1, adhesion regulating molecule 1

• This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Gene Synonyms (proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, M(r) 110,000 surface antigen, proteasome regulatory particle non-ATPase 13, proteasome ubiquitin receptor, rpn13 homolog, ARM-1, ARM1, GP110,)
• NCBI Gene ID: 11047
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16186
  UNIPROT ID#>>A0A087WX59
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adhesion regulating molecule 1 interacts with:

• adhesion regulating molecule 1
  ATPase H+ transporting V0 subunit d2
  autophagy related 16 like 1
  coiled-coil domain containing 74B
  coiled-coil domain containing 92
  egl-9 family hypoxia inducible factor 3
  FKBP prolyl isomerase 8
  insulin induced gene 2
  leucine rich repeat kinase 2
  limb development membrane protein 1 like
  obscurin like cytoskeletal adaptor 1
  pleckstrin homology domain containing A4
  proteasomal ATPase associated factor 1
  proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
  proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
  proteasome (prosome, macropain) subunit, beta type 4
  proteasome (prosome, macropain) subunit, beta type 5
  proteasome subunit alpha 2
  PTEN induced kinase 1
  ring finger protein 31
  SMAD specific E3 ubiquitin protein ligase 1
  TNFAIP3 interacting protein 2
  ubiquilin 1
  ubiquilin 2
  ubiquitin carboxyl-terminal esterase L5
  ubiquitin C-terminal hydrolase L5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.