ITGB1BP1, integrin subunit beta 1 binding protein 1

ITGB1BP1, integrin subunit beta 1 binding protein 1

• The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]

• Gene Synonyms (integrin beta-1-binding protein 1, bodenin, integrin cytoplasmic domain-associated protein 1, integrin cytoplasmic domain-associated protein 1-alpha, integrin cytoplasmic domain-associated protein 1-beta, ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B,)
• NCBI Gene ID: 9270
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DQY5
  UNIPROT ID#>>O14713
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrin subunit beta 1 binding protein 1 interacts with:

• CCM2 scaffold protein
  coiled-coil domain containing 33
  Fas associated factor 1
  fidgetin like 1
  progesterone receptor membrane component 1
  SMAD specific E3 ubiquitin protein ligase 1
  SMAD specific E3 ubiquitin protein ligase 2
  TRAF family member associated NFKB activator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.