CEBPZ, CCAAT enhancer binding protein zeta

CEBPZ, CCAAT enhancer binding protein zeta

• This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016]

• Gene Synonyms (CCAAT/enhancer-binding protein zeta, CCAAT-box-binding transcription factor, CCAAT/enhancer binding protein (C/EBP), zeta, CCAAT/enhancer binding protein cebp family zeta, CBF, CBF2, HSP-CBF, NOC1,)
• NCBI Gene ID: 10153
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q03701
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CCAAT enhancer binding protein zeta interacts with:

• centrosomal protein 164
  coiled-coil domain containing 59
  DEAD-box helicase 56
  EBNA1 binding protein 2
  F-box and WD repeat domain containing 7
  FMR1 neighbor
  G-patch domain containing 4
  GTP binding protein 4
  histone deacetylase 11
  La ribonucleoprotein 7, transcriptional regulator
  limb development membrane protein 1 like
  macroH2A.2 histone
  MAGE family member B10
  MAK16 homolog
  NOC2 like nucleolar associated transcriptional repressor
  NOP56 ribonucleoprotein
  nucleolar pre-rRNA processing protein NIP7
  obscurin like cytoskeletal adaptor 1
  peptidylprolyl isomerase E
  pescadillo ribosomal biogenesis factor 1
  pleckstrin homology domain containing A4
  PTEN induced kinase 1
  ribosomal protein S6 kinase A6
  ribosomal RNA processing 8
  RNA binding motif protein 34
  round spermatid basic protein 1
  sirtuin 7
  synaptotagmin binding cytoplasmic RNA interacting protein
  THAP domain containing 7
  tripartite motif containing 28
  YY1 associated protein 1
  zinc finger and BTB domain containing 7B
  zinc finger protein 512
  zinc finger protein 692
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.