PPIH, peptidylprolyl isomerase H

PPIH, peptidylprolyl isomerase H

• The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CYP-20, CYPH, SnuCyp-20, USA-CYP, peptidyl-prolyl cis-trans isomerase H, PPIase h, U-snRNP-associated cyclophilin SnuCyp-20, U-snRNP-associated cyclophilin SunCyp-20, USA-CyP SnuCyp-20, cyclophilin H, rotamase H, small nuclear ribonucleoprotein particle-specific cyclophilin H,)
• NCBI Gene ID: 10465
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FH36
  UNIPROT ID#>>O43447
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

peptidylprolyl isomerase H interacts with:

• B9 domain containing 2
  BPI fold containing family A member 1
  docking protein 3
  La ribonucleoprotein 7, transcriptional regulator
  ligand of numb-protein X 1
  ligand of numb-protein X 2
  LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM8 homolog, U6 small nuclear RNA associated
  methylphosphate capping enzyme
  methyltransferase like 18
  NGG1 interacting factor 3 like 1
  Obg like ATPase 1
  PAX interacting protein 1
  peptidylprolyl isomerase H
  pre-mRNA processing factor 31
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  RAD18 E3 ubiquitin protein ligase
  ribosomal protein L26 like 1
  ubiquilin 2
  zinc finger CCCH-type and G-patch domain containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.