PTP4A3, protein tyrosine phosphatase 4A3

PTP4A3, protein tyrosine phosphatase 4A3

• This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Gene Synonyms (protein tyrosine phosphatase type IVA 3, phosphatase of regenerating liver 3, potentially prenylated protein tyrosine phosphatase, protein tyrosine phosphatase type IVA, member 3, protein-tyrosine phosphatase of regenerating liver 3, PRL-3, PRL-R, PRL3,)
• NCBI Gene ID: 11156
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75365
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein tyrosine phosphatase 4A3 interacts with:

• ATPase family AAA domain containing 3A
  cyclin and CBS domain divalent metal cation transport mediator 3
  dicer 1, ribonuclease III
  dynein axonemal assembly factor 5
  Ecm29 proteasome adaptor and scaffold
  exportin 5
  exportin 7
  FA complementation group I
  fizzy and cell division cycle 20 related 1
  HEAT repeat containing 1
  importin 4
  kinesin family binding protein
  MMS19 homolog, cytosolic iron-sulfur assembly component
  non-SMC condensin I complex subunit G
  nucleoporin 188
  RAB3 GTPase activating non-catalytic protein subunit 2
  small ArfGAP 1
  SRP receptor subunit beta
  tetratricopeptide repeat domain 27
  transmembrane protein 33
  transportin 2
  ubiquitin conjugating enzyme E2 O
  ubiquitin protein ligase E3 component n-recognin 5
  valosin containing protein interacting protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.