ABCB8, ATP binding cassette subfamily B member 8

ABCB8, ATP binding cassette subfamily B member 8

• This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Gene Synonyms (mitochondrial potassium channel ATP-binding subunit, ATP-binding cassette sub-family B member 8, mitochondrial, ATP-binding cassette, sub-family B (MDR/TAP), member 8, mitochondrial ABC protein, mitochondrial ATP-binding cassette 1, mitochondrial sulfonylurea-receptor, EST328128, M-ABC1, MABC1, MITOSUR,)
• NCBI Gene ID: 11194
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NUT2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP binding cassette subfamily B member 8 interacts with:

• 3'(2'), 5'-bisphosphate nucleotidase 2
  adhesion G protein-coupled receptor G5
  ADP dependent glucokinase
  ATP binding cassette subfamily B member 8
  C-type lectin domain family 2 member D
  lactate dehydrogenase A like 6B
  mitochondrial transcription termination factor 3
  natural killer cell cytotoxicity receptor 3 ligand 1
  nitric oxide associated 1
  RAB11 family interacting protein 5
  signal peptide peptidase like 2B
  sodium voltage-gated channel beta subunit 3
  solute carrier family 2 member 12
  solute carrier family 39 member 9
  transmembrane protein 171
  V-set and immunoglobulin domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.