DAB1, DAB adaptor protein 1

DAB1, DAB adaptor protein 1

• The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]

• Gene Synonyms (disabled homolog 1, DAB1, reelin adaptor protein, Dab reelin signal transducer 1, Dab, reelin signal transducer, homolog 1, SCA37,)
• NCBI Gene ID: 1600
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75553
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DAB adaptor protein 1 interacts with:

• AT-rich interaction domain 5A
  basic helix-loop-helix family member e40
  chromosome 1 open reading frame 94
  circadian associated repressor of transcription
  CLK4 associating serine/arginine rich protein
  DAB2 interacting protein
  DAZ associated protein 2
  erb-b2 receptor tyrosine kinase 2
  erb-b2 receptor tyrosine kinase 3
  family with sequence similarity 168 member A
  galectin 9B
  galectin 9C
  heterogeneous nuclear ribonucleoprotein L
  heterogeneous nuclear ribonucleoprotein L like
  homeobox containing 1
  hyaluronidase 3
  inositol polyphosphate-5-phosphatase D
  integrin subunit beta 2
  integrin subunit beta 3
  integrin subunit beta 5
  integrin subunit beta 7
  keratin associated protein 19-5
  keratin associated protein 19-7
  keratin associated protein 8-1
  LDL receptor related protein 1
  LDL receptor related protein 2
  LDL receptor related protein 8
  ligand of numb-protein X 1
  low density lipoprotein receptor
  MAGE family member D1
  muscleblind like splicing regulator 1
  muscleblind like splicing regulator 3
  myosin VI
  N-terminal glutamine amidase 1
  nuclear assembly factor 1 ribonucleoprotein
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  peptidylprolyl isomerase G
  phospholipase C gamma 1
  platelet activating factor acetylhydrolase 1b regulatory subunit 1
  pogo transposable element derived with ZNF domain
  proline rich 20A
  protein tyrosine phosphatase non-receptor type 11
  protocadherin 18
  receptor tyrosine kinase like orphan receptor 2
  reelin
  Rhox homeobox family member 2
  RNA binding fox-1 homolog 1
  RNA binding fox-1 homolog 2
  RNA guanine-7 methyltransferase activating subunit
  SH3 domain containing kinase binding protein 1
  siah E3 ubiquitin protein ligase 1
  signal regulatory protein beta 1
  small ArfGAP2
  small EDRK-rich factor 2
  small nuclear ribonucleoprotein polypeptides B and B1
  spermatid perinuclear RNA binding protein
  SRC proto-oncogene, non-receptor tyrosine kinase
  suppressor of cytokine signaling 1
  suppressor of cytokine signaling 3
  suppressor of cytokine signaling 6
  suppressor of cytokine signaling 7
  toll interacting protein
  transcription elongation factor A N-terminal and central domain containing
  transcription elongation factor A2
  transmembrane O-mannosyltransferase targeting cadherins 3
  ubiquitin specific peptidase 53
  VENT homeobox
  very low density lipoprotein receptor
  zinc finger and BTB domain containing 32
  zinc finger CCCH-type containing 10
  zinc finger CCHC-type containing 10
  zinc finger protein 488

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.