SNRPB, small nuclear ribonucleoprotein polypeptides B and B1

SNRPB, small nuclear ribonucleoprotein polypeptides B and B1

• The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (small nuclear ribonucleoprotein-associated proteins B and B', B polypeptide of Sm protein, Sm protein B/B', sm-B/Sm-B', small nuclear ribonucleoprotein polypeptide B, small nuclear ribonucleoprotein polypeptides B and B', CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B,)
• NCBI Gene ID: 6628
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q66K91
  UNIPROT ID#>>P14678
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

small nuclear ribonucleoprotein polypeptides B and B1 interacts with:

• activating signal cointegrator 1 complex subunit 2
  A-kinase anchoring protein 9
  ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
  ariadne RBR E3 ubiquitin protein ligase 2
  BAG cochaperone 4
  BTG3 associated nuclear protein
  calcium binding and coiled-coil domain 2
  calcyclin binding protein
  catenin beta like 1
  CD2 cytoplasmic tail binding protein 2
  centrosomal protein 55
  cereblon
  coilin
  component of oligomeric golgi complex 6
  COP9 signalosome subunit 5
  CTD phosphatase subunit 1
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  cysteine rich tail 1
  cytochrome c oxidase assembly factor 7 (putative)
  DEAD-box helicase 20
  defective in cullin neddylation 1 domain containing 1
  DNA topoisomerase III beta
  E2F associated phosphoprotein
  elongation factor Tu GTP binding domain containing 2
  ergosterol biosynthesis 28 homolog
  erythrocyte membrane protein band 4.1 like 3
  eukaryotic translation initiation factor 4A3
  exosome component 8
  family with sequence similarity 168 member B
  far upstream element binding protein 1
  formin binding protein 4
  gem nuclear organelle associated protein 4
  gem nuclear organelle associated protein 5
  gem nuclear organelle associated protein 6
  gem nuclear organelle associated protein 7
  glutamate rich WD repeat containing 1
  GRB10 interacting GYF protein 1
  GRB10 interacting GYF protein 2
  growth factor independent 1B transcriptional repressor
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  hes related family bHLH transcription factor with YRPW motif 1
  HEXIM P-TEFb complex subunit 1
  HIV-1 Tat specific factor 1
  immunoglobulin superfamily member 8
  inhibitor of CDK, cyclin A1 interacting protein 1
  integrin alpha FG-GAP repeat containing 1
  keratin 40
  keratin associated protein 19-1
  keratin associated protein 19-6
  keratin associated protein 6-1
  keratin associated protein 6-2
  keratin associated protein 6-3
  L3MBTL histone methyl-lysine binding protein 3
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  lin-28 homolog A
  LSM11, U7 small nuclear RNA associated
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM8 homolog, U6 small nuclear RNA associated
  mediator of DNA damage checkpoint 1
  membrane associated guanylate kinase, WW and PDZ domain containing 2
  methyl-CpG binding domain protein 3 like 1
  methylphosphate capping enzyme
  methyltransferase like 14
  methyltransferase like 3
  Nanog homeobox
  neuronal calcium sensor 1
  NLR family pyrin domain containing 3
  nuclear receptor subfamily 2 group C member 2
  obscurin like cytoskeletal adaptor 1
  oocyte expressed protein
  Opa interacting protein 5
  pleckstrin homology domain containing B2
  PNMA family member 1
  poly(A) specific ribonuclease subunit PAN2
  PRAME nuclear receptor transcriptional regulator
  pre-mRNA processing factor 3
  pre-mRNA processing factor 31
  pre-mRNA processing factor 4B
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  proline rich 22
  protein arginine methyltransferase 5
  protein arginine methyltransferase 7
  protein arginine N-methyltransferase 5
  RecQ like helicase 4
  regulatory factor X6
  RIO kinase 1
  RNA binding protein, mRNA processing factor
  serine and arginine repetitive matrix 1
  serine/threonine kinase receptor associated protein
  SERTA domain containing 3
  SMAD specific E3 ubiquitin protein ligase 1
  small nuclear ribonucleoprotein 70 (U1)
  small nuclear ribonucleoprotein D1 polypeptide
  small nuclear ribonucleoprotein D2 polypeptide
  small nuclear ribonucleoprotein D3 polypeptide
  small nuclear ribonucleoprotein polypeptide C
  small nuclear ribonucleoprotein polypeptide E
  small nuclear ribonucleoprotein polypeptide F
  small nuclear ribonucleoprotein polypeptide G
  small nuclear ribonucleoprotein polypeptides B and B1
  small nuclear ribonucleoprotein U5 subunit 200
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  snurportin 1
  solute carrier family 7 member 6 opposite strand
  Sp3 transcription factor
  sperm associated antigen 8
  spliceosome associated factor 3, U4/U6 recycling protein
  splicing factor 3a subunit 2
  splicing factor 3a subunit 3
  splicing factor 3a, subunit 1
  SRSF protein kinase 2
  SRSF protein kinase 3
  SS18L1 subunit of BAF chromatin remodeling complex
  survival motor neuron 1
  survival motor neuron domain containing 1
  syntaxin binding protein 2
  syntaxin binding protein 3
  TATA-box binding protein associated factor 15
  TNF receptor associated factor 4
  transcription activation suppressor
  trimethylguanosine synthase 1
  tripartite motif containing 25
  tubulin beta class I
  tuftelin interacting protein 11
  tumor suppressing subtransferable candidate 4
  U1 small nuclear ribonucleoprotein C
  ubiquilin 2
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 M
  ubiquitin like modifier activating enzyme 2
  ubiquitin specific peptidase 54
  ubiquitin specific peptidase 9 X-linked
  UBX domain protein 11
  vir like m6A methyltransferase associated
  WD repeat domain 77
  WW domain binding protein 4
  WW domain containing E3 ubiquitin protein ligase 2
  Yes1 associated transcriptional regulator
  zinc finger CCCH-type and G-patch domain containing
  zinc finger protein 143

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.