CD2BP2, CD2 cytoplasmic tail binding protein 2

CD2BP2, CD2 cytoplasmic tail binding protein 2

• This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]

• Gene Synonyms (FWP010, LIN1, PPP1R59, Snu40, U5-52K, CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein 2, U5 snRNP 52K protein, protein phosphatase 1, regulatory subunit 59,)
• NCBI Gene ID: 10421
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95400
  UNIPROT ID#>>A0A024QZC1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD2 cytoplasmic tail binding protein 2 interacts with:

• AAR2 splicing factor
  acyl-CoA dehydrogenase family member 11
  adenosylhomocysteinase like 1
  AT-hook transcription factor
  carboxymethylenebutenolidase homolog
  CD2 cytoplasmic tail binding protein 2
  coactosin like F-actin binding protein 1
  CREB3 regulatory factor
  CWC22 spliceosome associated protein homolog
  DEAD-box helicase 20
  dermcidin
  DNA polymerase kappa
  E1A binding protein p400
  E2F associated phosphoprotein
  ecdysoneless cell cycle regulator
  egl-9 family hypoxia inducible factor 3
  gem nuclear organelle associated protein 4
  GINS complex subunit 3
  GINS complex subunit 4
  G-patch domain containing 8
  heterogeneous nuclear ribonucleoprotein U like 1
  HEXIM P-TEFb complex subunit 1
  HIV-1 Tat specific factor 1
  ISY1 splicing factor homolog
  karyopherin subunit alpha 6
  kelch like family member 36
  leucine rich repeat kinase 1
  MAX dimerization protein MGA
  N-alpha-acetyltransferase 30, NatC catalytic subunit
  N-alpha-acetyltransferase 35, NatC auxiliary subunit
  NEDD1 gamma-tubulin ring complex targeting factor
  nuclear RNA export factor 1
  nudix hydrolase 21
  obscurin like cytoskeletal adaptor 1
  paraspeckle component 1
  PAX interacting protein 1
  PHD finger protein 5A
  pleckstrin homology domain containing A4
  PNN interacting serine and arginine rich protein
  poly(U) binding splicing factor 60
  pre-mRNA processing factor 19
  pre-mRNA processing factor 31
  pre-mRNA processing factor 38B
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  proteasome maturation protein
  RAD18 E3 ubiquitin protein ligase
  RAD54 homolog B
  ring finger and CCCH-type domains 1
  RNA binding motif protein 42
  RNA polymerase III subunit C
  serine/arginine repetitive matrix 2
  SLU7 homolog, splicing factor
  small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  small nuclear ribonucleoprotein U5 subunit 200
  SMU1 DNA replication regulator and spliceosomal factor
  SNW domain containing 1
  splicing factor 3a subunit 3
  splicing factor 3b subunit 1
  splicing factor 3b subunit 2
  splicing factor 3b subunit 3
  squamous cell carcinoma antigen recognized by T cells 1
  target of EGR1, exonuclease
  TBL1X receptor 1
  thioredoxin like 4A
  TNF receptor associated factor 7
  trafficking protein particle complex 6A
  tubulin gamma complex associated protein 2
  tubulin gamma complex associated protein 3
  tubulin gamma complex associated protein 4
  tubulin gamma complex associated protein 5
  tubulin gamma complex associated protein 6
  U2 snRNP associated SURP domain containing
  ubiquilin 4
  ubiquitin specific peptidase 19
  ubiquitin specific peptidase 39
  vir like m6A methyltransferase associated
  WW domain binding protein 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.