TRAF7, TNF receptor associated factor 7

TRAF7, TNF receptor associated factor 7

• Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]

• Gene Synonyms (E3 ubiquitin-protein ligase TRAF7, RING finger and WD repeat-containing protein 1, RING finger protein 119, RING-type E3 ubiquitin transferase TRAF7, TNF receptor-associated factor 7, E3 ubiquitin protein ligase, ring finger and WD repeat domain 1, CAFDADD, RFWD1, RNF119,)
• NCBI Gene ID: 84231
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KQY7
  UNIPROT ID#>>Q6Q0C0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF receptor associated factor 7 interacts with:

• cingulin like 1
  deuterosome assembly protein 1
  G protein-coupled receptor 156
  IKBKB interacting protein
  lebercilin LCA5
  RALY RNA binding protein like
  TNF receptor associated factor 7
  TSPY like 6
  zinc finger protein 764

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.