PRPF3, pre-mRNA processing factor 3

PRPF3, pre-mRNA processing factor 3

• The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18. [provided by RefSeq, Jul 2008]

• Gene Synonyms (U4/U6 small nuclear ribonucleoprotein Prp3, PRP3 pre-mRNA processing factor 3 homolog, U4/U6 snRNP 90 kDa protein, U4/U6-associated RNA splicing factor, pre-mRNA-splicing factor 3, HPRP3, HPRP3P, PRP3, Prp3p, RP18, SNRNP90,)
• NCBI Gene ID: 9129
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43395
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pre-mRNA processing factor 3 interacts with:

• A-kinase anchoring protein 7
  Aly/REF export factor
  aurora kinase B
  BCAS2 pre-mRNA processing factor
  bromodomain containing 7
  caspase recruitment domain family member 10
  catenin beta like 1
  CD2 cytoplasmic tail binding protein 2
  centrosomal AT-AC splicing factor
  centrosomal protein 250
  centrosomal protein 70
  coiled-coil domain containing 125
  coiled-coil domain containing 136
  coiled-coil domain containing 85B
  coiled-coil-helix-coiled-coil-helix domain containing 2
  DEAD-box helicase 23
  DISC1 scaffold protein
  dpy-30 histone methyltransferase complex regulatory subunit
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 4A3
  family with sequence similarity 9 member B
  F-box protein 11
  FCH and mu domain containing endocytic adaptor 1
  FRA10A associated CGG repeat 1
  G protein-coupled receptor associated sorting protein 2
  GTP binding protein 3, mitochondrial
  heat shock transcription factor 2 binding protein
  hyaluronan binding protein 4
  ILK associated serine/threonine phosphatase
  kinesin associated protein 3
  La ribonucleoprotein 7, transcriptional regulator
  leucine zipper tumor suppressor 1
  lin-28 homolog A
  LSM1 homolog, mRNA degradation associated
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM8 homolog, U6 small nuclear RNA associated
  methylphosphate capping enzyme
  microtubule associated protein RP/EB family member 1
  midline 2
  MMS19 homolog, cytosolic iron-sulfur assembly component
  M-phase phosphoprotein 6
  neuron navigator 2
  NFKB activating protein
  nicotinamide nucleotide transhydrogenase
  ninein like
  NKAP domain containing 1
  NOP58 ribonucleoprotein
  nucleus accumbens associated 1
  Obg like ATPase 1
  obscurin like cytoskeletal adaptor 1
  oxysterol binding protein like 3
  PAT1 homolog 1, processing body mRNA decay factor
  peptidylprolyl isomerase H
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  polyglutamine binding protein 1
  pre-mRNA processing factor 19
  pre-mRNA processing factor 3
  pre-mRNA processing factor 31
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  pyrin and HIN domain family member 1
  RAB4B, member RAS oncogene family
  rabaptin, RAB GTPase binding effector protein 1
  RAD18 E3 ubiquitin protein ligase
  ribosomal protein L26 like 1
  ring finger and CCCH-type domains 2
  ring finger protein 151
  RIO kinase 1
  RNA binding motif protein 25
  RNA binding motif protein 26
  RNA binding motif protein 39
  RNA binding motif protein 42
  RNA binding protein with serine rich domain 1
  serine and arginine repetitive matrix 1
  serine/arginine repetitive matrix 2
  SERPINE1 mRNA binding protein 1
  SH3KBP1 binding protein 1
  SLU7 homolog, splicing factor
  Smad nuclear interacting protein 1
  small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  small nuclear ribonucleoprotein U5 subunit 200
  small nuclear ribonucleoprotein U5 subunit 40
  spliceosome associated factor 3, U4/U6 recycling protein
  splicing factor 3a subunit 1
  splicing factor 3a subunit 3
  splicing factor 3b subunit 1
  splicing factor 3b subunit 2
  splicing factor 3b subunit 3
  SPT16 homolog, facilitates chromatin remodeling subunit
  squamous cell carcinoma antigen recognized by T cells 1
  squamous cell carcinoma antigen recognized by T cells 3
  SSX family member 2 interacting protein
  survival motor neuron domain containing 1
  TAR DNA binding protein
  taxilin alpha
  terminal uridylyl transferase 1, U6 snRNA-specific
  thioredoxin like 4A
  thyroid hormone receptor associated protein 3
  transformer 2 alpha homolog
  tripartite motif containing 39
  tropomodulin 3
  tuftelin interacting protein 11
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin specific peptidase 15
  ubiquitin specific peptidase 39
  UTP20 small subunit processome component
  vir like m6A methyltransferase associated
  WW domain binding protein 4
  WW domain containing oxidoreductase
  XPA binding protein 2
  zinc finger and BTB domain containing 8A
  zinc finger CCCH-type and G-patch domain containing
  zinc finger CCHC-type containing 10
  zinc finger protein, FOG family member 2
  zinc finger RANBP2-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.