L3MBTL3, L3MBTL histone methyl-lysine binding protein 3

L3MBTL3, L3MBTL histone methyl-lysine binding protein 3

• This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]

• Gene Synonyms (lethal(3)malignant brain tumor-like protein 3, H-l(3)mbt-like protein 3, L3MBTL3, histone methyl-lysine binding protein, l(3)mbt-like 3, MBT-1, MBT1,)
• NCBI Gene ID: 84456
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96JM7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

L3MBTL histone methyl-lysine binding protein 3 interacts with:

• ankyrin repeat and SOCS box containing 6
  C1q and TNF related 4
  L3MBTL histone methyl-lysine binding protein 3
  L3MBTL histone methyl-lysine binding protein 4
  leucine rich repeat kinase 2
  SPANX family member N2
  sterile alpha motif domain containing 1
  sterile alpha motif domain containing 13
  thiosulfate sulfurtransferase like domain containing 2
  transcription elongation factor A N-terminal and central domain containing
  tubulin alpha 1c

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.