EPHB3, EPH receptor B3

EPHB3, EPH receptor B3

• Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]

• Gene Synonyms (EK2, ETK2, HEK2, TYRO6, ephrin type-B receptor 3, EPH-like tyrosine kinase 2, embryonic kinase 2, human embryo kinase 2, tyrosine-protein kinase TYRO6,)
• NCBI Gene ID: 2049
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P54753
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EPH receptor B3 interacts with:

• 1,4-alpha-glucan branching enzyme 1
  adhesion G protein-coupled receptor G5
  afadin, adherens junction formation factor
  EPH receptor B3
  erb-b2 receptor tyrosine kinase 2
  F-box protein 7
  FYN proto-oncogene, Src family tyrosine kinase
  heat shock transcription factor 2 binding protein
  hippocalcin like 1
  ligand of numb-protein X 1
  nuclear factor related to kappaB binding protein
  RAS p21 protein activator 1
  receptor like tyrosine kinase
  RUS family member 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.