GATM, glycine amidinotransferase

GATM, glycine amidinotransferase

• This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AGAT, AT, CCDS3, FRTS1, glycine amidinotransferase, mitochondrial, glycine amidinotransferase (L-arginine:glycine amidinotransferase), testicular secretory protein Li 19, transamidinase,)
• NCBI Gene ID: 2628
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VK19
  UNIPROT ID#>>P50440
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycine amidinotransferase interacts with:

• glycine amidinotransferase
  glycine amidinotransferase (L-arginine:glycine amidinotransferase)
  phosphodiesterase 4D interacting protein

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