GRIN2C, glutamate ionotropic receptor NMDA type subunit 2C

GRIN2C, glutamate ionotropic receptor NMDA type subunit 2C

• This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

• Gene Synonyms (glutamate receptor ionotropic, NMDA 2C, N-methyl D-aspartate receptor subtype 2C, N-methyl-D-aspartate receptor subunit 2C, glutamate [NMDA] receptor subunit epsilon-3, glutamate receptor, ionotropic, N-methyl D-aspartate 2C, GluN2C, NMDAR2C, NR2C,)
• NCBI Gene ID: 2905
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H0Y2V8
  UNIPROT ID#>>Q8IW23
  UNIPROT ID#>>O15398
  UNIPROT ID#>>Q14957
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutamate ionotropic receptor NMDA type subunit 2C interacts with:

• DLG associated protein 1
  erbb2 interacting protein
  interleukin 16
  PATJ crumbs cell polarity complex component

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.