IRF7, interferon regulatory factor 7

IRF7, interferon regulatory factor 7

• IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008]

• Gene Synonyms (IMD39, IRF-7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, interferon regulatory factor 7, interferon regulatory factor 7G isoform, interferon regulatory factor-7H,)
• NCBI Gene ID: 3665
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92985
  UNIPROT ID#>>M9RSF4
  UNIPROT ID#>>A0A024RCA2
  UNIPROT ID#>>B4E1B1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interferon regulatory factor 7 interacts with:

• aryl hydrocarbon receptor interacting protein
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chromatin assembly factor 1 subunit B
  coiled-coil domain containing 47
  DEAF1 transcription factor
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  DnaJ heat shock protein family (Hsp40) member B11
  elongation factor Tu GTP binding domain containing 2
  Fas associated via death domain
  glutaminyl-tRNA synthetase 1
  guanylate binding protein 4
  HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
  interferon regulatory factor 7
  IQ motif and Sec7 domain ArfGEF 1
  karyopherin subunit alpha 2
  listerin E3 ubiquitin protein ligase 1
  lysine acetyltransferase 2B
  MAF bZIP transcription factor B
  microtubule associated protein 1B
  mitochondrial antiviral signaling protein
  MYD88 innate immune signal transduction adaptor
  N-myc and STAT interactor
  OTU deubiquitinase 1
  phosphatase domain containing paladin 1
  prolyl 4-hydroxylase subunit alpha 1
  protein inhibitor of activated STAT 4
  Raf-1 proto-oncogene, serine/threonine kinase
  ring finger protein 31
  RNA polymerase II subunit B
  SMAD family member 2
  SMAD family member 3
  SMAD family member 4
  small ubiquitin like modifier 2
  small ubiquitin like modifier 3
  suppressor of cytokine signaling 1
  suppressor of cytokine signaling 3
  TANK binding kinase 1
  TARBP2 subunit of RISC loading complex
  t-complex 1
  TNF alpha induced protein 3
  TNF receptor associated factor 6
  toll like receptor adaptor molecule 1
  toll like receptor adaptor molecule 2
  tousled like kinase 2
  TRAF family member associated NFKB activator
  tripartite motif containing 21
  tripartite motif containing 28
  tRNA methyltransferase 2 homolog A
  tRNA methyltransferase 61B
  tubulin alpha 1c
  tubulin beta 2A class IIa
  tubulin beta 3 class III
  tumor protein p53
  vacuolar protein sorting 4 homolog A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.