KCNJ5, potassium inwardly rectifying channel subfamily J member 5

KCNJ5, potassium inwardly rectifying channel subfamily J member 5

• This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]

• Gene Synonyms (CIR, GIRK4, KATP1, KIR3.4, LQT13, G protein-activated inward rectifier potassium channel 4, IRK-4, cardiac ATP-sensitive potassium channel, heart KATP channel, inward rectifier K+ channel KIR3.4, potassium channel, inwardly rectifying subfamily J, member 5, potassium voltage-gated channel subfamily J member 5,)
• NCBI Gene ID: 3762
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48544
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium inwardly rectifying channel subfamily J member 5 interacts with:

• autophagy related 7
  ERI1 exoribonuclease family member 3
  G protein subunit beta 1 like
  G protein subunit beta 4
  LanC like 2
  LON peptidase N-terminal domain and ring finger 1
  myotubularin related protein 6
  nucleoporin 35
  phospholipase C gamma 1
  plakophilin 4
  potassium inwardly rectifying channel subfamily J member 15
  potassium inwardly rectifying channel subfamily J member 5
  WD repeat domain 45B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.