KCNMA1, potassium calcium-activated channel subfamily M alpha 1

KCNMA1, potassium calcium-activated channel subfamily M alpha 1

• MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (BKTM, CADEDS, IEG16, KCa1.1, LIWAS, MaxiK, PNKD3, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, hSlo, mSLO1, calcium-activated potassium channel subunit alpha-1, uncharacterized protein LOC3778, BK channel alpha subunit, BKCA alpha subunit, big potassium channel alpha subunit, calcium-activated potassium channel, subfamily M subunit alpha-1, k(VCA)alpha, maxi-K channel HSLO, potassium channel, calcium activated large conductance subfamily M alpha, member 1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, slo homolog, slowpoke homolog, stretch-activated Kca channel,)
• NCBI Gene ID: 3778
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A1W2PRN5
  UNIPROT ID#>>S4R453
  UNIPROT ID#>>D5MRH1
  UNIPROT ID#>>A0A087WZL8
  UNIPROT ID#>>A0A1W2PQU4
  UNIPROT ID#>>B7ZMF5
  UNIPROT ID#>>Q12791
  UNIPROT ID#>>A0A1W2PPY5
  UNIPROT ID#>>A0A1W2PP94
  UNIPROT ID#>>A0A1W2PR62
  UNIPROT ID#>>A0A1W2PSD3
  UNIPROT ID#>>Q5SVJ7
  UNIPROT ID#>>A0A1W2PQK5
  UNIPROT ID#>>A0A1W2PR56
  UNIPROT ID#>>Q59FH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium calcium-activated channel subfamily M alpha 1 interacts with:

• calcium voltage-gated channel subunit alpha1 H
  cereblon
  cullin 1
  embryonic ectoderm development
  F-box protein 7
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  microtubule associated protein 1A
  potassium calcium-activated channel subfamily M alpha 1
  potassium calcium-activated channel subfamily M regulatory beta subunit 1
  protein tyrosine kinase 2
  protein tyrosine phosphatase receptor type A
  S-phase kinase associated protein 1
  thromboxane A2 receptor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.