KCNQ3, potassium voltage-gated channel subfamily Q member 3

KCNQ3, potassium voltage-gated channel subfamily Q member 3

• This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

• Gene Synonyms (BFNC2, EBN2, KV7.3, potassium voltage-gated channel subfamily KQT member 3, potassium channel subunit alpha KvLQT3, potassium channel, voltage gated KQT-like subfamily Q, member 3, potassium channel, voltage-gated, subfamily Q, member 3, potassium voltage-gated channel, KQT-like subfamily, member 3, voltage-gated potassium channel subunit Kv7.3,)
• NCBI Gene ID: 3786
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43525
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium voltage-gated channel subfamily Q member 3 interacts with:

• potassium voltage-gated channel subfamily Q member 3
  potassium voltage-gated channel subfamily Q member 4
  potassium voltage-gated channel subfamily Q member 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.