MX2, MX dynamin like GTPase 2

MX2, MX dynamin like GTPase 2

• The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]

• Gene Synonyms (MXB, interferon-induced GTP-binding protein Mx2, interferon-regulated resistance GTP-binding protein MXB, myxovirus (influenza virus) resistance 2, myxovirus resistance protein 2, p78-related protein, second interferon-induced protein p78,)
• NCBI Gene ID: 4600
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P20592
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MX dynamin like GTPase 2 interacts with:

• ATR interacting protein
  cyclic GMP-AMP synthase
  euchromatic histone lysine methyltransferase 2
  MX dynamin like GTPase 2
  peroxiredoxin 5
  protein inhibitor of activated STAT 2
  thioredoxin
  thioredoxin 2
  thioredoxin domain containing 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.