MYBPC3, myosin binding protein C3

MYBPC3, myosin binding protein C3

• MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CMD1MM, CMH4, FHC, LVNC10, MYBP-C, cMyBP-C, myosin-binding protein C, cardiac-type, C-protein, cardiac muscle isoform, myosin binding protein C, cardiac, truncated cardiac myosin-binding protein C,)
• NCBI Gene ID: 4607
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A5YM48
  UNIPROT ID#>>Q14896
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin binding protein C3 interacts with:

• B cell linker
  cullin 1
  F-box protein 32
  myosin binding protein C3
  myosin heavy chain 9
  neutrophil cytosolic factor 1
  titin
  TNNI3 interacting kinase
  tripartite motif containing 55
  tripartite motif containing 63

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.