CHMP3, charged multivesicular body protein 3

CHMP3, charged multivesicular body protein 3

• This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]

• Gene Synonyms (charged multivesicular body protein 3, 25.1 protein, CHMP family, member 3, chromatin-modifying protein 3, neuroendocrine differentiation factor, vacuolar protein sorting 24 homolog, vacuolar protein sorting-associated protein 24, CGI-149, NEDF, VPS24,)
• NCBI Gene ID: 51652
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y3E7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

charged multivesicular body protein 3 interacts with:

• charged multivesicular body protein 1B
  charged multivesicular body protein 2A
  charged multivesicular body protein 3
  charged multivesicular body protein 4B
  charged multivesicular body protein 4B
  chromosome X open reading frame 56
  cyclic GMP-AMP synthase
  methylphosphate capping enzyme
  protein tyrosine phosphatase, non-receptor type 23

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.