TGIF2, TGFB induced factor homeobox 2

TGIF2, TGFB induced factor homeobox 2

• The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]

• Gene Synonyms (homeobox protein TGIF2, 5'-TG-3' interacting factor 2, TGF(beta)-induced transcription factor 2, TGFB-induced factor 2 (TALE family homeobox), transcription growth factor-beta-induced factor 2,)
• NCBI Gene ID: 60436
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9GZN2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TGFB induced factor homeobox 2 interacts with:

• TGFB induced factor homeobox 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.