RPL6, ribosomal protein L6

RPL6, ribosomal protein L6

• This gene encodes a protein component of the 60S ribosomal subunit. This protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

• Gene Synonyms (60S ribosomal protein L6, DNA-binding protein TAXREB107, large ribosomal subunit protein eL6, neoplasm-related protein C140, tax-responsive enhancer element-binding protein 107, L6, SHUJUN-2, TAXREB107, TXREB1,)
• NCBI Gene ID: 6128
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RBK3
  UNIPROT ID#>>Q8TBK5
  UNIPROT ID#>>Q02878
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ribosomal protein L6 interacts with:

• AAR2 splicing factor
  activator of HSP90 ATPase activity 1
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inhibitor 5
  ariadne RBR E3 ubiquitin protein ligase 2
  ATP binding cassette subfamily F member 2
  biogenesis of ribosomes BRX1
  bromodomain containing 4
  bromodomain containing 7
  CCHC-type zinc finger nucleic acid binding protein
  CD2-associated protein
  CDGSH iron sulfur domain 1
  centrosomal protein 250
  charged multivesicular body protein 4B
  clathrin heavy chain like 1
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  CTD small phosphatase like 2
  cullin 1
  cullin 2
  cullin 3
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  DDB1 and CUL4 associated factor 1
  DEAD-box helicase 24
  death associated protein 3
  defective in cullin neddylation 1 domain containing 1
  developmental pluripotency-associated 3
  DExD-box helicase 21
  EBNA1 binding protein 2
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 3, subunit E
  eukaryotic translation initiation factor 4A3
  exportin 1
  F-box protein 6
  F-box protein 7
  forty-two-three domain containing 1
  FtsJ RNA 2'-O-methyltransferase 3
  G protein nucleolar 3
  GDNF inducible zinc finger protein 1
  glutamate rich WD repeat containing 1
  GTP binding protein 4
  H2A clustered histone 4
  H3 clustered histone 1
  H4 clustered histone 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  immunoglobulin superfamily member 8
  influenza virus NS1A binding protein
  inhibitor of Bruton tyrosine kinase
  innate immunity activator
  INO80 complex subunit B
  insulin like growth factor 2 mRNA binding protein 3
  integrin alpha FG-GAP repeat containing 1
  Kin17 DNA and RNA binding protein
  KRI1 homolog
  KRR1 small subunit processome component homolog
  La ribonucleoprotein 1, translational regulator
  La ribonucleoprotein 7, transcriptional regulator
  lin-28 homolog B
  listerin E3 ubiquitin protein ligase 1
  MAGE family member B10
  magnesium transporter 1
  matrin 3
  Max protein
  metadherin
  methyl-CpG binding domain protein 2
  methylphosphate capping enzyme
  methyltransferase like 14
  mitochondrial carrier 2
  mitochondrial ribosomal protein L13
  mitochondrial ribosomal protein L15
  mitochondrial ribosomal protein L24
  mitochondrial ribosomal protein L27
  mitochondrial ribosomal protein L30
  mitochondrial ribosomal protein L34
  mitochondrial ribosomal protein L38
  mitochondrial ribosomal protein L42
  mitochondrial ribosomal protein L45
  mitochondrial ribosomal protein L46
  mitochondrial ribosomal protein L47
  mitochondrial ribosomal protein L9
  mitochondrial ribosomal protein S11
  mitochondrial ribosomal protein S14
  mitochondrial ribosomal protein S18A
  mitochondrial ribosomal protein S18C
  mitochondrial ribosomal protein S2
  mitochondrial ribosomal protein S21
  mitochondrial ribosomal protein S22
  mitochondrial ribosomal protein S23
  mitochondrial ribosomal protein S24
  mitochondrial ribosomal protein S26
  mitochondrial ribosomal protein S27
  mitochondrial ribosomal protein S30
  mitochondrial ribosomal protein S31
  mitochondrial ribosomal protein S33
  mitochondrial ribosomal protein S34
  mitochondrial ribosomal protein S35
  mitochondrial ribosomal protein S5
  mitochondrial ribosomal protein S7
  mitochondrial ribosomal protein S9
  mitochondrial transcription termination factor 3
  mitogen-activated protein kinase kinase kinase 14
  MYB binding protein 1a
  myosin, heavy polypeptide 9, non-muscle
  NADH:ubiquinone oxidoreductase complex assembly factor 8
  neugrin, neurite outgrowth associated
  NOP56 ribonucleoprotein
  NOP58 ribonucleoprotein
  nuclear cap binding subunit 3
  nuclear receptor binding SET domain protein 2
  nuclear receptor subfamily 2 group C member 2
  nucleolar and coiled-body phosphoprotein 1
  nucleoporin 98
  obscurin like cytoskeletal adaptor 1
  PC4 and SFRS1 interacting protein 1
  pentatricopeptide repeat domain 1
  pentatricopeptide repeat domain 3
  peptidylprolyl isomerase E
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  poly(A) specific ribonuclease subunit PAN2
  poly(U) binding splicing factor 60
  potassium channel modulatory factor 1
  potassium channel tetramerization domain containing 10
  pre-mRNA processing factor 8
  pyrin and HIN domain family member 1
  RALY heterogeneous nuclear ribonucleoprotein
  RecQ like helicase 4
  ribosomal protein L10
  ribosomal protein L10 like
  ribosomal protein L11
  ribosomal protein L12
  ribosomal protein L13
  ribosomal protein L13a
  ribosomal protein L14
  ribosomal protein L15
  ribosomal protein L17
  ribosomal protein L18
  ribosomal protein L18a
  ribosomal protein L19
  ribosomal protein L21
  ribosomal protein L22
  ribosomal protein L23
  ribosomal protein L23a
  ribosomal protein L24
  ribosomal protein L26
  ribosomal protein L26 like 1
  ribosomal protein L27
  ribosomal protein L27a
  ribosomal protein L28
  ribosomal protein L29
  ribosomal protein L30
  ribosomal protein L31
  ribosomal protein L32
  ribosomal protein L34
  ribosomal protein L35
  ribosomal protein L35a
  ribosomal protein L36
  ribosomal protein L37a
  ribosomal protein L38
  ribosomal protein L7
  ribosomal protein L7a
  ribosomal protein L8
  ribosomal protein L9
  ribosomal protein lateral stalk subunit P0
  ribosomal protein lateral stalk subunit P1
  ribosomal protein lateral stalk subunit P2
  ribosomal protein S10
  ribosomal protein S11
  ribosomal protein S12
  ribosomal protein S13
  ribosomal protein S14
  ribosomal protein S15
  ribosomal protein S15a
  ribosomal protein S16
  ribosomal protein S17
  ribosomal protein S18
  ribosomal protein S19
  ribosomal protein S2
  ribosomal protein S20
  ribosomal protein S21
  ribosomal protein S23
  ribosomal protein S24
  ribosomal protein S25
  ribosomal protein S26
  ribosomal protein S27
  ribosomal protein S27 like
  ribosomal protein S27a
  ribosomal protein S28
  ribosomal protein S3
  ribosomal protein S3A
  ribosomal protein S4 X-linked
  ribosomal protein S5
  ribosomal protein S6
  ribosomal protein S6 kinase B2
  ribosomal protein S7
  ribosomal protein S8
  ribosomal protein S9
  ribosomal RNA processing 12 homolog
  ribosome binding protein 1
  ribosome biogenesis regulator 1 homolog
  ring-box 1
  RIO kinase 1
  RNA binding motif protein 34
  RNA binding protein with serine rich domain 1
  SEC61 translocon subunit beta
  SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
  serine and arginine rich splicing factor 10
  serine/arginine repetitive matrix 2
  signal recognition particle 14
  signal recognition particle 72
  sirtuin 1
  sirtuin 7
  small nuclear ribonucleoprotein U1 subunit 70
  snail family transcriptional repressor 1
  spindle apparatus coiled-coil protein 1
  spliceosome associated factor 3, U4/U6 recycling protein
  staufen double-stranded RNA binding protein 1
  staufen double-stranded RNA binding protein 2
  surfeit 6
  survival of motor neuron 1, telomeric
  TAR DNA binding protein
  testis expressed 101
  THO complex 5
  thymopoietin
  thyroid hormone receptor interactor 11
  thyroid hormone receptor interactor 4
  TPX2, microtubule-associated
  transcription factor CP2
  transformer 2 alpha homolog
  translocated promoter region, nuclear basket protein
  tripartite motif containing 25
  tripartite motif containing 3
  Tu translation elongation factor, mitochondrial
  tubulin gamma 1
  tumor necrosis factor
  tumor protein p53
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  U2 small nuclear RNA auxiliary factor 2
  ubiquinol-cytochrome c reductase binding protein
  ubiquitin like 4A
  ubiquitin specific peptidase 14
  valosin containing protein
  von Hippel-Lindau tumor suppressor
  VRK serine/threonine kinase 1
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  Y-box binding protein 3
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 11
  zinc finger CCCH-type containing 18
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.