RPL27, ribosomal protein L27

RPL27, ribosomal protein L27

• Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]

• Gene Synonyms (60S ribosomal protein L27, large ribosomal subunit protein eL27, DBA16, L27,)
• NCBI Gene ID: 6155
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61353
  UNIPROT ID#>>A0A024R1V4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ribosomal protein L27 interacts with:

• AAR2 splicing factor
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inhibitor 5
  argonaute RISC component 4
  ariadne RBR E3 ubiquitin protein ligase 2
  aurora kinase A
  autophagy related 16 like 1
  biogenesis of ribosomes BRX1
  cap methyltransferase 1
  CCCTC-binding factor
  CCHC-type zinc finger nucleic acid binding protein
  centrosomal protein 250
  cereblon
  coenzyme Q2, polyprenyltransferase
  COP9 signalosome subunit 5
  cullin 1
  cullin 2
  cullin 3
  cullin 4B
  cullin 5
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 18
  DEAD-box helicase 56
  developmental pluripotency-associated 3
  dynamin 1 like
  EBNA1 binding protein 2
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 3, subunit A
  eukaryotic translation initiation factor 3, subunit E
  GAR1 ribonucleoprotein
  GTP binding protein 4
  H3 clustered histone 6
  H4 clustered histone 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 4
  hypoxia inducible factor 1 subunit alpha inhibitor
  immunoglobulin superfamily member 8
  INO80 complex subunit B
  integrin alpha FG-GAP repeat containing 1
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  LEO1 homolog, Paf1/RNA polymerase II complex component
  lysine rich nucleolar protein 1
  matrin 3
  methylphosphate capping enzyme
  methyltransferase like 14
  mitochondrial ribosomal protein L22
  MRT4 homolog, ribosome maturation factor
  NEDD1 gamma-tubulin ring complex targeting factor
  neuropilin 1
  NOC2 like nucleolar associated transcriptional repressor
  NSA2 ribosome biogenesis factor
  nuclear cap binding subunit 3
  nuclear receptor subfamily 2 group C member 2
  par-6 family cell polarity regulator beta
  pelota mRNA surveillance and ribosome rescue factor
  peptidylprolyl isomerase E
  pescadillo ribosomal biogenesis factor 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  poly(A) specific ribonuclease subunit PAN2
  pre-mRNA processing factor 8
  PTEN induced kinase 1
  pumilio RNA binding family member 3
  RecQ like helicase 4
  ribosomal protein L10 like
  ribosomal protein L13a
  ribosomal protein L14
  ribosomal protein L23
  ribosomal protein L26 like 1
  ribosomal protein L27
  ribosomal protein L27a
  ribosomal protein L28
  ribosomal protein L30
  ribosomal protein L31
  ribosomal protein L32
  ribosomal protein L34
  ribosomal protein L35
  ribosomal protein L35
  ribosomal protein L35a
  ribosomal protein L36
  ribosomal protein L37
  ribosomal protein L37a
  ribosomal protein L38
  ribosomal protein lateral stalk subunit P0
  ribosomal protein lateral stalk subunit P1
  ribosomal protein lateral stalk subunit P2
  ribosomal protein S10
  ribosomal protein S11
  ribosomal protein S12
  ribosomal protein S13
  ribosomal protein S14
  ribosomal protein S15
  ribosomal protein S15a
  ribosomal protein S16
  ribosomal protein S17
  ribosomal protein S18
  ribosomal protein S19
  ribosomal protein S2
  ribosomal protein S20
  ribosomal protein S21
  ribosomal protein S23
  ribosomal protein S24
  ribosomal protein S25
  ribosomal protein S26
  ribosomal protein S27
  ribosomal protein S29
  ribosomal protein S3
  ribosomal protein S3A
  ribosomal protein S4 X-linked
  ribosomal protein S5
  ribosomal protein S6
  ribosomal protein S6 kinase B2
  ribosomal protein S7
  ribosomal protein S8
  ribosomal protein S9
  ribosome binding protein 1
  ribosome biogenesis regulator 1 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  small nuclear ribonucleoprotein U1 subunit 70
  snail family transcriptional repressor 1
  SPANX family member N2
  spindle apparatus coiled-coil protein 1
  spliceosome associated factor 3, U4/U6 recycling protein
  SRY-box transcription factor 2
  staufen double-stranded RNA binding protein 1
  sterol O-acyltransferase 1
  thymopoietin
  transcription factor CP2
  treacle ribosome biogenesis factor 1
  tripartite motif containing 25
  tubulin gamma complex associated protein 4
  tumor necrosis factor
  tumor protein p53
  ubiquitin conjugating enzyme E2 L6
  ubiquitin like 4A
  voltage dependent anion channel 1
  VRK serine/threonine kinase 1
  WW domain containing E3 ubiquitin protein ligase 2
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 1
  zinc finger and BTB domain containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.