SRSF6, serine and arginine rich splicing factor 6

SRSF6, serine and arginine rich splicing factor 6

• The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

• Gene Synonyms (serine/arginine-rich splicing factor 6, SR splicing factor 6, epididymis secretory protein Li 91, pre-mRNA-splicing factor SRP55, splicing factor, arginine/serine-rich, 55 kDa, B52, HEL-S-91, SFRS6, SRP55,)
• NCBI Gene ID: 6431
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13247
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine and arginine rich splicing factor 6 interacts with:

• ankyrin repeat and SOCS box containing 18
  atlastin GTPase 3
  bromodomain containing 7
  cap methyltransferase 1
  CD2 cytoplasmic tail binding protein 2
  COP9 signalosome subunit 5
  cullin 1
  cullin 2
  cullin 7
  cullin associated and neddylation dissociated 1
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  eukaryotic translation initiation factor 3 subunit I
  eukaryotic translation initiation factor 4A3
  exportin 1
  expressed sequence AI837181
  H4 clustered histone 1
  HEXIM P-TEFb complex subunit 1
  IQ motif containing GTPase activating protein 1
  La ribonucleoprotein 7, transcriptional regulator
  leucine zipper protein 4
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  methyltransferase like 14
  nuclear receptor subfamily 2 group C member 2
  obscurin like cytoskeletal adaptor 1
  peptidylprolyl isomerase E
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  PPARG coactivator 1 alpha
  pre-mRNA processing factor 38A
  RecQ like helicase 4
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ribosomal RNA processing 1B
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring-box 1
  RIO kinase 1
  RNA binding motif protein 10
  RNA binding protein with serine rich domain 1
  serine and arginine repetitive matrix 1
  serine and arginine rich splicing factor 10
  serine and arginine rich splicing factor 7
  serine and arginine rich splicing factor 9
  Smad nuclear interacting protein 1
  small nuclear ribonucleoprotein U1 subunit 70
  SNW domain containing 1
  splicing factor 3a subunit 2
  splicing factor 3b subunit 4
  splicing regulatory glutamic acid and lysine rich protein 1
  SRSF protein kinase 1
  SRSF protein kinase 2
  SRSF protein kinase 3
  staufen double-stranded RNA binding protein 1
  SUB1 regulator of transcription
  SUZ12 polycomb repressive complex 2 subunit
  TAR DNA binding protein
  target of EGR1, exonuclease
  TATA-box binding protein associated factor 15
  telomeric repeat binding factor 1
  telomeric repeat binding factor 2
  thymopoietin
  TNFAIP3 interacting protein 2
  transformer 2 alpha homolog
  transformer 2 beta homolog
  trinucleotide repeat containing adaptor 6A
  tumor necrosis factor
  tumor protein p53
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  U2 small nuclear RNA auxiliary factor 2
  VRK serine/threonine kinase 1
  WW domain containing E3 ubiquitin protein ligase 2
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.