SNRPA, small nuclear ribonucleoprotein polypeptide A

SNRPA, small nuclear ribonucleoprotein polypeptide A

• The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]

• Gene Synonyms (U1 small nuclear ribonucleoprotein A, U1 small nuclear RNP-specific A, U1 snRNP A, U1 snRNP-specific protein A, Mud1, U1-A, U1A,)
• NCBI Gene ID: 6626
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09012
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

small nuclear ribonucleoprotein polypeptide A interacts with:

• AAR2 splicing factor
  adenosylhomocysteinase like 1
  agmatinase
  ariadne RBR E3 ubiquitin protein ligase 2
  chromatin target of PRMT1
  complexin 1
  COP9 signalosome subunit 5
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  DAZ associated protein 1
  DExD-box helicase 39B
  DNA damage inducible transcript 4 like
  ecto-NOX disulfide-thiol exchanger 2
  eEF1A lysine and N-terminal methyltransferase
  embryonic ectoderm development
  exportin 1
  far upstream element binding protein 1
  F-box protein 7
  GIT ArfGAP 1
  GRB10 interacting GYF protein 1
  H2A clustered histone 4
  H3 clustered histone 1
  H4 clustered histone 1
  HEXIM P-TEFb complex subunit 1
  La ribonucleoprotein 7, transcriptional regulator
  leukocyte receptor cluster member 8
  ligand of numb-protein X 1
  LIM homeobox 4
  lin-28 homolog A
  lin-28 homolog B
  matrin 3
  microtubule associated scaffold protein 2
  mitochondrial ribosomal protein L15
  muscleblind like splicing regulator 2
  NADH:ubiquinone oxidoreductase complex assembly factor 3
  nuclear receptor subfamily 2 group C member 2
  obscurin like cytoskeletal adaptor 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) polymerase alpha
  poly(rC) binding protein 3
  polypyrimidine tract binding protein 2
  pre-mRNA processing factor 19
  pre-mRNA processing factor 6
  QKI, KH domain containing RNA binding
  RAD18 E3 ubiquitin protein ligase
  RAS protein activator like 3
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RIO kinase 1
  RNA binding motif protein 11
  RNA binding motif protein 42
  RNA binding motif protein 4B
  RNA binding motif protein X-linked
  RNA binding motif protein Y-linked family 1 member F
  RNA binding motif protein Y-linked family 1 member J
  RNA binding protein with serine rich domain 1
  RNA binding protein, mRNA processing factor 2
  serine and arginine rich splicing factor 11
  SMAD specific E3 ubiquitin protein ligase 1
  small nuclear ribonucleoprotein polypeptide A
  small nuclear ribonucleoprotein polypeptide A'
  small nuclear ribonucleoprotein polypeptide C
  small nuclear ribonucleoprotein polypeptide E
  small nuclear ribonucleoprotein polypeptide F
  small nuclear ribonucleoprotein polypeptide G
  small nuclear ribonucleoprotein polypeptide N
  splicing factor 3a subunit 1
  splicing factor 3a subunit 2
  splicing factor 3a subunit 3
  splicing factor 3b subunit 1
  splicing factor 3b subunit 3
  splicing factor 3b subunit 5
  SRSF protein kinase 2
  SRSF protein kinase 3
  SUZ12 polycomb repressive complex 2 subunit
  TATA-box binding protein associated factor 15
  telomerase RNA component interacting RNase
  thiosulfate sulfurtransferase
  TIA1 cytotoxic granule associated RNA binding protein like 1
  TNF alpha induced protein 8 like 1
  TNFAIP3 interacting protein 2
  transcriptional adaptor 2A
  translocase of inner mitochondrial membrane 13
  tripartite motif containing 24
  tumor protein p63
  tyrosyl-tRNA synthetase 1
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin C
  WW domain binding protein 4
  zinc finger CCHC-type containing 13

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.