SSR3, signal sequence receptor subunit 3

SSR3, signal sequence receptor subunit 3

• The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010]

• Gene Synonyms (translocon-associated protein subunit gamma, SSR gamma, TRAP-complex gamma subunit, TRAP-gamma, signal sequence receptor subunit gamma, signal sequence receptor, gamma (translocon-associated protein gamma), translocon-associated protein gamma subunit, TRAPG,)
• NCBI Gene ID: 6747
• Species: Homo sapiens (Human)
• UNIPROT ID#>>C9J365
  UNIPROT ID#>>Q9UNL2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

signal sequence receptor subunit 3 interacts with:

• assembly factor for spindle microtubules
  ATP synthase membrane subunit g
  BRISC and BRCA1 A complex member 2
  centriolin
  centrosomal protein 164
  centrosomal protein 44
  cysteine and histidine rich domain containing 1
  DExD-box helicase 21
  DExD-box helicase 39A
  DExD-box helicase 39B
  dynein cytoplasmic 1 light intermediate chain 1
  egl-9 family hypoxia inducible factor 3
  ER lipid raft associated 1
  family with sequence similarity 162 member A
  H4 clustered histone 1
  hydroxysteroid 17-beta dehydrogenase 12
  hypoxia inducible factor 1 subunit alpha inhibitor
  integrin beta 1 (fibronectin receptor beta)
  kelch like family member 29
  limb development membrane protein 1 like
  magnesium transporter 1
  myosin heavy chain 14
  nuclear receptor subfamily 2 group C member 2
  pleckstrin homology domain containing A4
  proline rich coiled-coil 2A
  protein arginine methyltransferase 7
  protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  protocadherin beta 15
  Rab acceptor 1
  RAB5 interacting factor
  reticulon 4
  Rho-associated coiled-coil containing protein kinase 1
  ribosomal protein L14
  SEC61 translocon subunit alpha 1
  sequestosome 1
  signal sequence receptor subunit 4
  Sin3A associated protein 18
  sodium channel and clathrin linker 1
  solute carrier family 6 (neurotransmitter transporter, creatine), member 8
  splicing factor 3b subunit 1
  splicing factor 3b subunit 3
  staphylococcal nuclease and tudor domain containing 1
  tectonic family member 2
  tectonic family member 3
  transcription elongation factor A like 1
  translocase of outer mitochondrial membrane 22
  transmembrane and coiled-coil domains 1
  tripartite motif containing 14
  tripartite motif containing 25
  tripartite motif containing 28
  tubulin, gamma 1
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin specific peptidase 43
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  WW domain containing oxidoreductase
  X-ray repair cross complementing 3
  Yip1 domain family member 5
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.