NDUFAF5, NADH:ubiquinone oxidoreductase complex assembly factor 5

NDUFAF5, NADH:ubiquinone oxidoreductase complex assembly factor 5

• The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes a mitochondrial protein that is associated with the matrix face of the mitochondrial inner membrane and is required for complex I assembly. A mutation in this gene results in mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Gene Synonyms (arginine-hydroxylase NDUFAF5, mitochondrial, NADH dehydrogenase (ubiquinone) complex I, assembly factor 5, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5, probable methyltransferase C20orf7, mitochondrial, putative methyltransferase NDUFAF5, C20orf7, MC1DN16, bA526K24.2, dJ842G6.1,)
• NCBI Gene ID: 79133
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5TEU4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NADH:ubiquinone oxidoreductase complex assembly factor 5 interacts with:

• bolA family member 3
  deltex E3 ubiquitin ligase 3
  GrpE like 2, mitochondrial
  kelch like family member 22
  methyltransferase like 2A
  mitochondrial ribosomal protein L21
  mitochondrial ribosomal protein L43
  mitochondrial rRNA methyltransferase 1
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  NADH:ubiquinone oxidoreductase complex assembly factor 8
  NADH:ubiquinone oxidoreductase core subunit S7
  oxidoreductase like domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.