COLQ, collagen like tail subunit of asymmetric acetylcholinesterase

COLQ, collagen like tail subunit of asymmetric acetylcholinesterase

• This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (acetylcholinesterase collagenic tail peptide, AChE Q subunit, acetylcholinesterase-associated collagen, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase, collagenic tail of endplate acetylcholinesterase, single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase, CMS5, EAD,)
• NCBI Gene ID: 8292
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y215
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collagen like tail subunit of asymmetric acetylcholinesterase interacts with:

• cartilage associated protein
  collagen beta(1-O)galactosyltransferase 2
  prolyl 3-hydroxylase 1
  prolyl 3-hydroxylase 2
  prolyl 3-hydroxylase 3
  prolyl 3-hydroxylase family member 4 (inactive)
  small glutamine rich tetratricopeptide repeat containing beta
  testis expressed 15, meiosis and synapsis associated
  tripartite motif containing 68

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.