CDC42BPA, CDC42 binding protein kinase alpha

CDC42BPA, CDC42 binding protein kinase alpha

• The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]

• Gene Synonyms (serine/threonine-protein kinase MRCK alpha, CDC42 binding protein kinase alpha (DMPK-like), CDC42 binding protein kinase beta, myotonic dystrophy kinase-related CDC42-binding protein kinase alpha, myotonic dystrophy protein kinase-like alpha, ser-thr protein kinase PK428, ser-thr protein kinase related to the myotonic dystrophy protein kinase, MRCK, MRCKA, PK428,)
• NCBI Gene ID: 8476
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5VT25
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CDC42 binding protein kinase alpha interacts with:

• catenin, beta like 1
  CDC42 binding protein kinase alpha
  centromere protein Q
  CTD small phosphatase like 2
  family with sequence similarity 167 member A
  inka box actin regulator 2
  INO80 complex subunit B
  kinesin family member 20B
  leucine rich adaptor protein 1 like
  leucine rich repeat containing G protein-coupled receptor 4
  myosin light chain 9
  pleckstrin homology domain containing A4
  potassium channel tetramerization domain containing 17
  protein phosphatase 1 regulatory subunit 12C
  rabaptin, RAB GTPase binding effector protein 2
  RNA binding motif protein 8A
  RuvB-like protein 2
  SIN3-HDAC complex associated factor
  spindle and kinetochore associated complex subunit 3
  spire type actin nucleation factor 2
  squamous cell carcinoma antigen recognized by T cells 1
  tubulin tyrosine ligase-like family, member 7
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.