SPAG9, sperm associated antigen 9

SPAG9, sperm associated antigen 9

• This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

• Gene Synonyms (C-Jun-amino-terminal kinase-interacting protein 4, JNK interacting protein, JNK/SAPK-associated protein, Max-binding protein, c-Jun NH2-terminal kinase-associated leucine zipper protein, cancer/testis antigen 89, human lung cancer oncogene 6 protein, lung cancer oncogene 4, mitogen-activated protein kinase 8-interacting protein 4, proliferation-inducing gene 6, protein highly expressed in testis, sperm associated antigen 9 variant 5, sperm surface protein, sunday driver 1, CT89, HLC-6, HLC4, HLC6, JIP-4, JIP4, JLP, PHET, PIG6,)
• NCBI Gene ID: 9043
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JB53
  UNIPROT ID#>>O60271
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sperm associated antigen 9 interacts with:

• abraxas 2, BRISC complex subunit
  acyl-CoA thioesterase 12
  ADP ribosylation factor GTPase activating protein 1
  autophagy related 2B
  baculoviral IAP repeat containing 7
  bMERB domain containing 1
  BRCA1/BRCA2-containing complex subunit 3
  calcium voltage-gated channel auxiliary subunit gamma 5
  catechol-O-methyltransferase domain containing 1
  CD2 associated protein
  chromobox 8
  cyclin dependent kinase 11A
  epidermal growth factor receptor pathway substrate 15 like 1
  family with sequence similarity 174 member A
  family with sequence similarity 219 member B
  general transcription factor IIIC subunit 4
  GTPase activating protein and VPS9 domains 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  influenza virus NS1A binding protein
  kelch like family member 40
  kinesin family member 16B
  La ribonucleoprotein 7, transcriptional regulator
  mediator complex subunit 4
  mediator complex subunit 9
  meiotic nuclear divisions 1
  melanoregulin
  metastasis associated 1 family member 2
  microtubule associated protein 1 light chain 3 beta
  mitogen-activated protein kinase 8 interacting protein 3
  neudesin neurotrophic factor
  N-myc downstream regulated 1
  nucleolar and coiled-body phosphoprotein 1
  pleckstrin homology domain containing A4
  polo like kinase 1
  proline rich nuclear receptor coactivator 2
  protein phosphatase 4 regulatory subunit 2
  protein phosphatase 4 regulatory subunit 3A
  protein phosphatase, Mg2+/Mn2+ dependent 1K
  PTEN induced kinase 1
  RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
  rabaptin, RAB GTPase binding effector protein 2
  RCC1 domain containing 1
  ribonucleotide reductase regulatory TP53 inducible subunit M2B
  ring finger protein 123
  single-pass membrane protein with coiled-coil domains 1
  sirtuin 7
  sperm associated antigen 9
  strawberry notch homolog 1
  structural maintenance of chromosomes 3
  thioredoxin domain containing 9
  TNFAIP3 interacting protein 2
  transmembrane protein 44
  ubiquitin specific peptidase 15
  vasorin
  vir like m6A methyltransferase associated
  zinc finger BED-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.