DEDD, death effector domain containing

DEDD, death effector domain containing

• This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (death effector domain-containing protein, DEDPro1, FLDED-1, death effector domain-containing testicular molecule, CASP8IP1, DEDD1, DEFT, FLDED1, KE05,)
• NCBI Gene ID: 9191
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B1AQP5
  UNIPROT ID#>>O75618
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

death effector domain containing interacts with:

• basic leucine zipper ATF-like transcription factor 2
  coiled-coil domain containing 59
  death effector domain containing
  death effector domain containing 2
  F-box protein 38
  general transcription factor IIIC subunit 3
  nuclear RNA export factor 1
  ubiquitin specific peptidase 22

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.