PRPF4B, pre-mRNA processing factor 4B

PRPF4B, pre-mRNA processing factor 4B

• Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]

• Gene Synonyms (serine/threonine-protein kinase PRP4 homolog, PRP4 kinase, PRP4 pre-mRNA processing factor 4 homolog B, PRP4 pre-mRNA-processing factor 4 homolog, dJ1013A10.1 (PRP4 protein kinase homolog), protein-serine/threonine kinase, PR4H, PRP4, PRP4H, PRP4K, dJ1013A10.1,)
• NCBI Gene ID: 8899
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13523
  UNIPROT ID#>>A0A024QZY5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pre-mRNA processing factor 4B interacts with:

• A-kinase anchoring protein 5
  bromodomain containing 7
  CD2 cytoplasmic tail binding protein 2
  cell division cycle 6
  DEAD-box helicase 23
  deuterosome assembly protein 1
  elongation factor Tu GTP binding domain containing 2
  erythrocyte membrane protein band 4.1 like 3
  exportin 1
  FANCD2 and FANCI associated nuclease 1
  heat shock protein family B (small) member 3
  hyaluronan binding protein 4
  kinesin family member 1C
  Kruppel like factor 13
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  macroH2A.2 histone
  NKAP domain containing 1
  nuclear cap binding protein subunit 2
  nucleolar protein interacting with the FHA domain of MKI67
  nudix hydrolase 21
  obscurin like cytoskeletal adaptor 1
  pleckstrin homology domain containing A4
  pre-mRNA processing factor 31
  pre-mRNA processing factor 4
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  PTEN induced kinase 1
  RAD18 E3 ubiquitin protein ligase
  ribosomal protein L14
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ribosomal RNA processing 1B
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RNA binding motif protein 34
  RNA binding protein with serine rich domain 1
  RNA polymerase III subunit F
  serine/arginine repetitive matrix 2
  SERPINE1 mRNA binding protein 1
  sirtuin 7
  small nuclear ribonucleoprotein U5 subunit 200
  small nuclear ribonucleoprotein U5 subunit 40
  spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
  SPT16 homolog, facilitates chromatin remodeling subunit
  squamous cell carcinoma antigen recognized by T cells 3
  SRSF protein kinase 3
  ubiquitin specific peptidase 39
  vir like m6A methyltransferase associated
  zinc finger CCCH-type containing 18
  zinc finger RANBP2-type containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.