DLG2, discs large MAGUK scaffold protein 2

DLG2, discs large MAGUK scaffold protein 2

• This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]

• Gene Synonyms (disks large homolog 2, DLG2 protein isoform, channel-associated protein of synapse-110, channel-associated protein of synapses, 110kDa, discs, large homolog 2, chapsyn-110, postsynaptic density protein PSD-93, protein phosphatase 1, regulatory subunit 58, PPP1R58, PSD-93, PSD93, chapsyn-110,)
• NCBI Gene ID: 1740
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15700
  UNIPROT ID#>>B7Z2T4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

discs large MAGUK scaffold protein 2 interacts with:

• calcium voltage-gated channel auxiliary subunit gamma 2
  connector enhancer of kinase suppressor of Ras 2
  CXXC repeat containing interactor of PDZ3 domain
  discs large MAGUK scaffold protein 2
  discs large MAGUK scaffold protein 4
  DLG associated protein 1
  DLG associated protein 2
  DLG associated protein 3
  dynein light chain LC8-type 1
  dynein light chain LC8-type 2
  erb-b2 receptor tyrosine kinase 4
  fatty acid 2-hydroxylase
  frizzled class receptor 1
  frizzled class receptor 4
  frizzled class receptor 7
  glutamate ionotropic receptor delta type subunit 1
  glutamate ionotropic receptor delta type subunit 2
  glutamate ionotropic receptor NMDA type subunit 1
  glutamate ionotropic receptor NMDA type subunit 2A
  glutamate ionotropic receptor NMDA type subunit 2B
  glutamate ionotropic receptor NMDA type subunit 2D
  glutaminase 2
  guanylate cyclase 1 soluble subunit alpha 2
  KDEL endoplasmic reticulum protein retention receptor 1
  KH RNA binding domain containing, signal transduction associated 1
  kinesin family member 1B
  KRAS proto-oncogene, GTPase
  LDL receptor related protein 2
  lin-7 homolog A, crumbs cell polarity complex component
  microtubule associated protein 1A
  mitogen-activated protein kinase 12
  neuroligin 1
  neuroligin 2
  neuroligin 3
  nitric oxide synthase 1
  peptidylprolyl isomerase like 4
  pleckstrin homology domain containing A2
  potassium inwardly rectifying channel subfamily J member 12
  potassium inwardly rectifying channel subfamily J member 2
  potassium inwardly rectifying channel subfamily J member 4
  potassium voltage-gated channel subfamily A member 4
  proteasome 26S subunit, non-ATPase 14
  ribonuclease A family member 2
  ribosomal protein S8
  ribosome production factor 2 homolog
  semaphorin 4C
  serpin family B member 13
  sodium voltage-gated channel alpha subunit 4
  sodium voltage-gated channel alpha subunit 5
  vitronectin
  Wnt family member 3A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.