HMGN2, high mobility group nucleosomal binding domain 2

HMGN2, high mobility group nucleosomal binding domain 2

• The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]

• Gene Synonyms (non-histone chromosomal protein HMG-17, high mobility group nucleosome-binding domain-containing protein 2, high mobility group protein N2, high-mobility group (nonhistone chromosomal) protein 17, nonhistone chromosomal protein HMG-17, HMG17,)
• NCBI Gene ID: 3151
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P05204
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

high mobility group nucleosomal binding domain 2 interacts with:

• autophagy related 16 like 1
  charged multivesicular body protein 1A
  decapping enzyme, scavenger
  glycogen phosphorylase B
  H2A clustered histone 11
  H3 clustered histone 1
  H4 clustered histone 1
  high mobility group nucleosomal binding domain 2
  histone PARylation factor 1
  kelch like family member 36
  KRAS proto-oncogene, GTPase
  lysine acetyltransferase 2B
  macroH2A.1 histone
  melatonin receptor 1A
  mitogen-activated protein kinase 6
  MYC proto-oncogene, bHLH transcription factor
  nuclear receptor subfamily 2 group C member 2
  poly(ADP-ribose) polymerase 2
  protein kinase C alpha
  protein kinase cAMP-activated catalytic subunit alpha
  ribosomal protein S6 kinase A3
  SRSF protein kinase 2
  telomeric repeat binding factor 2
  ubiquitin C
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 14

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.