ITGA1, integrin subunit alpha 1

ITGA1, integrin subunit alpha 1

• This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CD49a, VLA1, integrin alpha-1, CD49 antigen-like family member A, VLA-1, laminin and collagen receptor, very late activation protein 1,)
• NCBI Gene ID: 3672
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P56199
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrin subunit alpha 1 interacts with:

• casein kinase 1, delta
  DISC1 scaffold protein
  galectin 3
  galectin 8
  glucosamine-phosphate N-acetyltransferase 1
  HCLS1 associated X-1
  integrin beta 1 (fibronectin receptor beta)
  integrin subunit alpha 1
  integrin subunit beta 1
  IQ motif containing GTPase activating protein 3
  laminin subunit alpha 1
  lectin, mannose binding 2 like
  LIM domain kinase 1
  mago homolog, exon junction complex core component
  matrilin 1
  protein tyrosine phosphatase 4A3
  protein tyrosine phosphatase non-receptor type 2
  protein tyrosine phosphatase non-receptor type 6
  SHANK associated RH domain interactor
  SMC5-SMC6 complex localization factor 2
  talin 1
  TIMP metallopeptidase inhibitor 2
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.