MYL2, myosin light chain 2

MYL2, myosin light chain 2

• Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CMH10, MLC-2s/v, MLC2, myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v, RLC of myosin, cardiac myosin light chain 2, cardiac ventricular myosin light chain 2, myosin light chain 2, slow skeletal/ventricular muscle isoform, myosin, light chain 2, regulatory, cardiac, slow, myosin, light polypeptide 2, regulatory, cardiac, slow, regulatory light chain of myosin, slow cardiac myosin regulatory light chain 2, ventricular myosin light chain 2,)
• NCBI Gene ID: 4633
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P10916
  UNIPROT ID#>>Q6IB42
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin light chain 2 interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  assembly factor for spindle microtubules
  CDC42 binding protein kinase alpha
  interleukin 36 gamma
  leucine rich repeat and sterile alpha motif containing 1
  myocilin
  myosin light chain 5
  myosin VA
  myosin VB
  myosin XIX
  NHP2 ribonucleoprotein
  p21 (RAC1) activated kinase 2
  protein phosphatase 1 regulatory subunit 12C
  psoriasis susceptibility 1 candidate 2
  pyruvate kinase M1/2
  Rho associated coiled-coil containing protein kinase 2
  tripartite motif containing 55
  tripartite motif containing 63
  ubiquitin specific peptidase 6
  zinc finger protein 529

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.