PPP2CB, protein phosphatase 2 catalytic subunit beta

PPP2CB, protein phosphatase 2 catalytic subunit beta

• This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]

• Gene Synonyms (serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, PP2A-beta, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isozyme, protein phosphatase 2A catalytic subunit, beta isoform, protein phosphatase type 2A catalytic subunit, serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform, testicular tissue protein Li 146, PP2Abeta, PP2CB,)
• NCBI Gene ID: 5516
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P62714
  UNIPROT ID#>>A0A140VJS0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 2 catalytic subunit beta interacts with:

• 2,4-dienoyl-CoA reductase 2
  actin beta like 2
  alanyl-tRNA synthetase domain containing 1
  ankyrin repeat and LEM domain containing 2
  ankyrin repeat and SOCS box containing 5
  autophagy related 7
  axin 1
  basic helix-loop-helix family member e41
  calmodulin regulated spectrin associated protein family member 3
  centrosomal protein 131
  centrosomal protein 350
  centrosomal protein 43
  centrosomal protein 43
  centrosomal protein 72
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chromobox 5
  chromosome 22 open reading frame 39
  coiled-coil domain containing 6
  coiled-coil domain containing 61
  cortactin binding protein 2
  CTTNBP2 N-terminal like
  cullin 4A
  dedicator of cytokinesis 7
  dynein light chain LC8-type 1
  E1A binding protein p400
  elaC ribonuclease Z 2
  family with sequence similarity 122A
  family with sequence similarity 122B
  F-box and leucine rich repeat protein 16
  F-box and leucine-rich repeat protein 16
  FGFR1 oncogene partner 2
  histone deacetylase 5
  integrator complex subunit 1
  integrator complex subunit 11
  integrator complex subunit 12
  integrator complex subunit 2
  integrator complex subunit 3
  integrator complex subunit 4
  integrator complex subunit 5
  integrator complex subunit 6
  integrator complex subunit 9
  L3MBTL histone methyl-lysine binding protein 3
  La ribonucleoprotein 7, transcriptional regulator
  leucine carboxyl methyltransferase 1
  microtubule affinity regulating kinase 4
  microtubule associated protein 7
  mitogen-activated protein kinase kinase kinase kinase 4
  MOB family member 4, phocein
  myosin light chain, phosphorylatable, fast skeletal muscle
  NADH:ubiquinone oxidoreductase complex assembly factor 1
  NGG1 interacting factor 3 like 1
  nitric oxide synthase interacting protein
  NOP2/Sun RNA methyltransferase 2
  phosphofurin acidic cluster sorting protein 1
  pleckstrin homology domain containing A4
  pleckstrin homology domain containing A5
  plexin A3
  prefoldin subunit 6
  programmed cell death 10
  proline rich 14
  proline rich 14 like
  protein kinase C beta
  protein kinase N3
  protein phosphatase 2 phosphatase activator
  protein phosphatase 2 regulatory subunit Balpha
  protein phosphatase 2 regulatory subunit B'alpha
  protein phosphatase 2 regulatory subunit Bbeta
  protein phosphatase 2 regulatory subunit B''beta
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 2 regulatory subunit B'delta
  protein phosphatase 2 regulatory subunit B'epsilon
  protein phosphatase 2 regulatory subunit Bgamma
  protein phosphatase 2 regulatory subunit B'gamma
  protein phosphatase 2 regulatory subunit B''gamma
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase 2 scaffold subunit Abeta
  protein phosphatase 2, regulatory subunit A, alpha
  protein phosphatase 2, regulatory subunit B, delta
  protein phosphatase 4 catalytic subunit
  protein phosphatase 4 regulatory subunit 1
  protein phosphatase 4 regulatory subunit 3B
  protein phosphatase methylesterase 1
  PTPRF interacting protein alpha 1
  PTPRF interacting protein alpha 3
  Raf-1 proto-oncogene, serine/threonine kinase
  RELA proto-oncogene, NF-kB subunit
  Rho/Rac guanine nucleotide exchange factor 2
  ribosomal protein lateral stalk subunit P1
  RIO kinase 1
  sarcolemma associated protein
  serine/threonine kinase 24
  serine/threonine kinase 25
  serine/threonine kinase 26
  SERTA domain containing 4
  SET nuclear proto-oncogene
  shugoshin 1
  shugoshin 2A
  snail family transcriptional repressor 1
  snail family transcriptional repressor 2
  striatin
  striatin 3
  striatin 4
  striatin interacting protein 1
  striatin interacting protein 2
  striatin, calmodulin binding protein 3
  suppressor of IKBKE 1
  TBC1 domain family member 4
  TBCC domain containing 1
  t-complex 1
  Tctex1 domain containing 2
  telomeric repeat binding factor 1
  tetratricopeptide repeat domain 1
  tetratricopeptide repeat domain 33
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  TOR signaling pathway regulator
  transmembrane protein 41B
  tripartite motif containing 25
  tripartite motif containing 28
  tRNA methyltransferase 61B
  URI1 prefoldin like chaperone
  valosin containing protein
  VHL binding protein 1
  WD repeat domain 12
  WD repeat domain 61
  ZFP28 zinc finger protein
  ZFP36 ring finger protein
  zinc finger protein 444
  zinc finger protein 775

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.