SNAI2, snail family transcriptional repressor 2

SNAI2, snail family transcriptional repressor 2

• This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

• Gene Synonyms (zinc finger protein SNAI2, neural crest transcription factor SLUG, protein snail homolog 2, slug (chicken homolog), zinc finger protein, snail family zinc finger 2, snail homolog 2, SLUG, SLUGH, SLUGH1, SNAIL2, WS2D,)
• NCBI Gene ID: 6591
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43623
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

snail family transcriptional repressor 2 interacts with:

• calcium binding protein 2
  F-box protein 31
  lysine demethylase 1A
  nuclear RNA export factor 1
  protein inhibitor of activated STAT 1
  protein inhibitor of activated STAT 2
  protein inhibitor of activated STAT 3
  protein inhibitor of activated STAT 4
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 6 regulatory subunit 3
  SIN3 transcription regulator family member A
  STIP1 homology and U-box containing protein 1
  SUMO specific peptidase 1
  SUMO specific peptidase 2
  tight junction protein 2
  transcriptional regulator, SIN3A (yeast)
  tumor protein p53
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 10
  ubiquitin specific peptidase 17 like family member 2
  ubiquitin specific peptidase 5
  zinc finger protein 76

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.