PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta

PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta

• The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015]

• Gene Synonyms (cAMP-dependent protein kinase type I-beta regulatory subunit, protein kinase, cAMP-dependent, regulatory subunit type I beta, protein kinase, cAMP-dependent, regulatory, type I, beta, PRKAR1,)
• NCBI Gene ID: 5575
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P31321
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein kinase cAMP-dependent type I regulatory subunit beta interacts with:

• A-kinase anchoring protein 1
  A-kinase anchoring protein 14
  A-kinase anchoring protein 7
  ankyrin repeat and sterile alpha motif domain containing 1A
  BAG cochaperone 3
  BAG cochaperone 6
  biorientation of chromosomes in cell division 1 like 2
  calmodulin regulated spectrin associated protein 1
  cell division cycle 37, HSP90 cochaperone
  centrosomal protein 19
  chromobox 8
  chromosome 6 open reading frame 141
  coiled-coil domain containing 103
  coiled-coil domain containing 187
  cullin 3
  dihydrouridine synthase 3 like
  DNA cross-link repair 1C
  DNA polymerase epsilon 4, accessory subunit
  egl-9 family hypoxia inducible factor 3
  erythroblast membrane associated protein (Scianna blood group)
  eukaryotic elongation factor 2 kinase
  eukaryotic elongation factor 2 lysine methyltransferase
  exportin 1
  FAM161 centrosomal protein A
  family with sequence similarity 90 member A1
  FCH and double SH3 domains 2
  G protein nucleolar 3 like
  G protein-coupled receptor 161
  GLIS family zinc finger 2
  glutamine rich 1
  G-patch domain and KOW motifs
  growth arrest specific 2 like 2
  immunoglobulin like and fibronectin type III domain containing 1
  inositol polyphosphate-5-phosphatase J
  KN motif and ankyrin repeat domains 2
  L3MBTL histone methyl-lysine binding protein 2
  leukocyte receptor cluster member 1
  ligand of numb-protein X 1
  mediator complex subunit 8
  methyl-CpG binding domain protein 3
  mitochondrial ribosomal protein S15
  myosin XVB
  NADPH oxidase 5
  NSF attachment protein gamma
  N-terminal glutamine amidase 1
  nuclear RNA export factor 1
  phosphoinositide-3-kinase regulatory subunit 3
  phosphoribosyl pyrophosphate synthetase associated protein 2
  pre-mRNA processing factor 18
  proteasome assembly chaperone 1
  protein kinase cAMP-dependent type I regulatory subunit beta
  protein kinase cAMP-dependent type II regulatory subunit beta
  protein kinase, cAMP dependent, catalytic, beta
  protein phosphatase 1 regulatory subunit 9A
  Rab geranylgeranyltransferase subunit beta
  Rap guanine nucleotide exchange factor 5
  retinoic acid receptor gamma
  SAP30 binding protein
  secreted frizzled related protein 4
  serine/threonine kinase 16
  SH2 domain containing 4A
  SHC adaptor protein 3
  SMG9 nonsense mediated mRNA decay factor
  SNW domain containing 1
  S-phase kinase associated protein 2
  synaptotagmin 11
  synaptotagmin like 4
  TEA domain transcription factor 4
  testis specific 10 interacting protein
  thyroid hormone receptor alpha
  transcription activation suppressor family member 2
  tripartite motif containing 25
  tRNA-histidine guanylyltransferase 1 like
  uveal autoantigen with coiled-coil domains and ankyrin repeats
  VAMP associated protein A
  VAMP associated protein B and C
  vascular endothelial zinc finger 1
  WNK lysine deficient protein kinase 1
  WRN RecQ like helicase
  zinc finger and BTB domain containing 16
  zinc finger MYND-type containing 19
  zinc finger protein 177
  zinc finger protein 329
  zinc finger protein 35
  zinc finger protein 410
  zinc finger protein 76
  ZNF559-ZNF177 readthrough

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.