MFHAS1, malignant fibrous histiocytoma amplified sequence 1

MFHAS1, malignant fibrous histiocytoma amplified sequence 1

• Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]

• Gene Synonyms (malignant fibrous histiocytoma-amplified sequence 1, MFH-amplified sequences with leucine-rich tandem repeats 1, leucine rich repeat containing 65, malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1, malignant fibrous histiocytoma-amplified sequences with leucine-rich tandem repeats 1, LRRC65, MASL1, ROCO4,)
• NCBI Gene ID: 9258
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y4C4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

malignant fibrous histiocytoma amplified sequence 1 interacts with:

• adenosylhomocysteinase like 1
  ankyrin repeat and sterile alpha motif domain containing 4B
  ankyrin repeat domain 13A
  ankyrin repeat domain 13D
  apurinic/apyrimidinic endodeoxyribonuclease 2
  AT-hook DNA binding motif containing 1
  BAG cochaperone 2
  calcium binding protein 4
  CCAAT enhancer binding protein zeta
  CDC42 effector protein 3
  cell cycle regulator of NHEJ
  centromere protein O
  centrosomal protein 85
  coiled-coil domain containing 149
  coiled-coil domain containing 22
  coiled-coil domain containing 43
  COPI coat complex subunit beta 2
  CREB regulated transcription coactivator 2
  CUE domain containing 1
  DNA damage inducible 1 homolog 1
  DNA polymerase alpha 2, accessory subunit
  DNA polymerase iota
  dynein regulatory complex subunit 3
  egl-9 family hypoxia inducible factor 2
  gametocyte specific factor 1
  gasdermin D
  GC-rich promoter binding protein 1 like 1
  growth arrest specific 2 like 3
  HIC ZBTB transcriptional repressor 2
  intraflagellar transport associated protein
  kelch domain containing 4
  kinesin family member 3A
  LIM domain and actin binding 1
  MRG domain binding protein
  NIMA related kinase 11
  praja ring finger ubiquitin ligase 2
  progesterone receptor membrane component 2
  proteasome activator subunit 3 interacting protein 1
  protein kinase AMP-activated non-catalytic subunit gamma 2
  RAS like family 11 member B
  rhomboid domain containing 1
  RNA polymerase II associated protein 3
  selenoprotein S
  serine/threonine kinase 25
  smoothelin like 2
  solute carrier family 4 member 1 adaptor protein
  STIP1 homology and U-box containing protein 1
  STN1 subunit of CST complex
  taste 2 receptor member 60
  TBC1 domain family member 22B
  tetratricopeptide repeat domain 27
  TNFAIP3 interacting protein 2
  TOX high mobility group box family member 2
  transcriptional adaptor 3
  transmembrane protein 132A
  tripartite motif containing 22
  ubiquitin like 7
  vestigial like family member 4
  vir like m6A methyltransferase associated
  vomeronasal 1 receptor 1
  WW domain containing transcription regulator 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.