FKBP3, FKBP prolyl isomerase 3

FKBP3, FKBP prolyl isomerase 3

• The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]

• Gene Synonyms (FKBP-25, FKBP-3, FKBP25, PPIase, peptidyl-prolyl cis-trans isomerase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FK506 binding protein 3, 25kDa, FK506-binding protein 25, T-cell, FK506-binding protein 3, PPIase FKBP3, immunophilin FKBP25, rapamycin binding protein, rapamycin-selective 25 kDa immunophilin, rotamase,)
• NCBI Gene ID: 2287
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q00688
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FKBP prolyl isomerase 3 interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  autophagy related 16 like 1
  centrosomal protein 19
  CGG triplet repeat binding protein 1
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  dynein light chain LC8-type 1
  elongation factor Tu GTP binding domain containing 2
  enhancer of mRNA decapping 4
  eukaryotic translation initiation factor 2B subunit beta
  eukaryotic translation initiation factor 2B subunit gamma
  F-box protein 25
  heterogeneous nuclear ribonucleoprotein A2/B1
  heterogeneous nuclear ribonucleoprotein U
  histidine triad nucleotide binding protein 2
  histone deacetylase 1
  histone deacetylase 2
  insulin like growth factor 2 mRNA binding protein 3
  interleukin enhancer binding factor 2
  keratin 18
  LRR binding FLII interacting protein 1
  MDM2 proto-oncogene
  metastasis associated 1 family member 2
  microtubule associated protein 1S
  microtubule associated protein tau
  myosin heavy chain 10
  NEDD4 E3 ubiquitin protein ligase
  NEDD4 like E3 ubiquitin protein ligase
  negative elongation factor complex member B
  neurotrophic receptor tyrosine kinase 1
  N-myristoyltransferase 1
  peptidylprolyl isomerase A
  protein kinase C and casein kinase substrate in neurons 3
  replication factor C subunit 4
  RNA transcription, translation and transport factor
  SEC16 homolog A, endoplasmic reticulum export factor
  SMAD specific E3 ubiquitin protein ligase 1
  SRSF protein kinase 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  timeless circadian regulator
  tumor protein p53
  Y-box binding protein 1
  YKT6 v-SNARE homolog
  YY1 transcription factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.