PPP1CB, protein phosphatase 1 catalytic subunit beta

PPP1CB, protein phosphatase 1 catalytic subunit beta

• The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

• Gene Synonyms (serine/threonine-protein phosphatase PP1-beta catalytic subunit, epididymis secretory sperm binding protein Li 80p, myosin phosphatase, protein phosphatase 1, catalytic subunit, beta isoform, protein phosphatase 1, catalytic subunit, beta isozyme, protein phosphatase 1, catalytic subunit, delta isoform, protein phosphatase 1-beta, protein phosphatase 1-delta, HEL-S-80p, MP, NSLH2, PP-1B, PP1B, PP1beta, PP1c, PPP1CD, PPP1beta,)
• NCBI Gene ID: 5500
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HW04
  UNIPROT ID#>>P62140
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 1 catalytic subunit beta interacts with:

• actin filament associated protein 1
  actin related protein 2
  actin related protein 2/3 complex subunit 2
  actin related protein 2/3 complex subunit 4
  actin related protein 3
  actin related protein T1
  A-kinase anchoring protein 11
  anillin actin binding protein
  anoctamin 7
  anti-silencing function 1A histone chaperone
  apolipoprotein B mRNA editing enzyme catalytic subunit 3B
  apoptosis associated tyrosine kinase
  armadillo repeat containing 8
  arrestin, beta 2
  ATP binding cassette subfamily E member 1
  aurora kinase A
  autophagy related 16 like 1
  BMP2 inducible kinase
  brain abundant membrane attached signal protein 1
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  calmodulin-like 3
  CD2 cytoplasmic tail binding protein 2
  cell division cycle associated 2
  centrosomal protein 72
  chaperonin containing TCP1 subunit 8
  chromosome 14 open reading frame 180
  chromosome 20 open reading frame 27
  clathrin interactor 1
  cleavage and polyadenylation specific factor 1
  clock circadian regulator
  coiled-coil domain containing 85C
  coiled-coil-helix-coiled-coil-helix domain containing 3
  cordon-bleu WH2 repeat protein
  coronin 1B
  coronin 1C
  cullin 3
  cysteine and serine rich nuclear protein 1
  cysteine and serine rich nuclear protein 2
  cysteine rich tail 1
  DDB1 and CUL4 associated factor 7
  DENN domain containing 2B
  density regulated re-initiation and release factor
  destrin, actin depolymerizing factor
  dynein light chain LC8-type 2
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  F-box and WD repeat domain containing 7
  F-box protein 7
  glutamate rich WD repeat containing 1
  growth arrest specific 2 like 1
  growth arrest specific 2 like 3
  H2A clustered histone 4
  H3 clustered histone 1
  H4 clustered histone 1
  histone deacetylase 7
  integrator complex subunit 1
  integrator complex subunit 6
  integrin alpha 5 (fibronectin receptor alpha)
  inturned planar cell polarity protein
  inverted formin 2
  IQ motif containing GTPase activating protein 1
  ITPR interacting domain containing 2
  KH RNA binding domain containing, signal transduction associated 1
  KIAA1671
  kinesin family member 18A
  kinesin family member 18B
  KN motif and ankyrin repeat domains 2
  La ribonucleoprotein 7, transcriptional regulator
  lemur tyrosine kinase 2
  leucine rich repeat containing 1
  leucine zipper like transcription regulator 1
  leucine zipper protein 1
  leucine zipper protein 4
  LIM and calponin homology domains 1
  LIM domain and actin binding 1
  lysine acetyltransferase 8
  matrin 3
  mediator complex subunit 23
  methyltransferase like 17
  mitotic spindle positioning
  multiple inositol-polyphosphate phosphatase 1
  myosin IC
  myosin phosphatase Rho interacting protein
  myosin VC
  myosin XIX
  myosin XVIIIA
  myosin, heavy polypeptide 10, non-muscle
  myosin, heavy polypeptide 9, non-muscle
  nexilin F-actin binding protein
  NUAK family kinase 1
  nuclear receptor coactivator 5
  nuclear receptor corepressor 1
  O-linked N-acetylglucosamine (GlcNAc) transferase
  p53 and DNA damage regulated 1
  PALM2 and AKAP2 fusion
  phosphatase and actin regulator 3
  phosphofurin acidic cluster sorting protein 1
  phospholipase C like 2
  PIH1 domain containing 1
  pleckstrin homology and RhoGEF domain containing G3
  pleckstrin homology domain containing A4
  poly(A) polymerase alpha
  poly(A) specific ribonuclease subunit PAN2
  polyglutamine binding protein 1
  PPP1R2 family member B
  PPP1R2C family member C
  PR/SET domain 16
  progesterone receptor membrane component 1
  protein kinase cAMP-dependent type II regulatory subunit alpha
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 1 regulatory inhibitor subunit 11
  protein phosphatase 1 regulatory inhibitor subunit 2
  protein phosphatase 1 regulatory subunit 10
  protein phosphatase 1 regulatory subunit 12C
  protein phosphatase 1 regulatory subunit 13 like
  protein phosphatase 1 regulatory subunit 13B
  protein phosphatase 1 regulatory subunit 15A
  protein phosphatase 1 regulatory subunit 15B
  protein phosphatase 1 regulatory subunit 16A
  protein phosphatase 1 regulatory subunit 16B
  protein phosphatase 1 regulatory subunit 18
  protein phosphatase 1 regulatory subunit 27
  protein phosphatase 1 regulatory subunit 37
  protein phosphatase 1 regulatory subunit 3A
  protein phosphatase 1 regulatory subunit 3C
  protein phosphatase 1 regulatory subunit 7
  protein phosphatase 1 regulatory subunit 8
  protein phosphatase 1 regulatory subunit 9B
  protein phosphatase 1, regulatory subunit 10
  protein phosphatase 1, regulatory subunit 7
  protein phosphatase 2 regulatory subunit B'gamma
  protein phosphatase 6 catalytic subunit
  protein tyrosine kinase 2
  Rac GTPase activating protein 1
  RAD18 E3 ubiquitin protein ligase
  RAR related orphan receptor C
  Ras association domain family member 7
  Ras association domain family member 8
  Ras association domain family member 9
  RB transcriptional corepressor 1
  RBMX like 1
  RE1 silencing transcription factor
  regulatory associated protein of MTOR complex 1
  replication timing regulatory factor 1
  retinoic acid induced 14
  Rho GTPase activating protein 11A
  Rho GTPase activating protein 21
  ribosomal RNA processing 1B
  ring finger protein 144A
  RNA binding motif protein 12B
  RNA binding motif protein 6
  RNA binding motif protein X-linked
  RNA polymerase II associated protein 3
  ryanodine receptor 2
  SAS-6 centriolar assembly protein
  scaffold attachment factor B
  scaffold attachment factor B2
  scribble planar cell polarity protein
  SEC16 homolog A, endoplasmic reticulum export factor
  secreted frizzled related protein 1
  secreted frizzled related protein 2
  secreted frizzled related protein 5
  SH2 domain containing 4A
  SHOC2 leucine rich repeat scaffold protein
  signal induced proliferation associated 1 like 3
  signal-induced proliferation-associated 1
  sirtuin 2
  sirtuin 7
  slingshot protein phosphatase 2
  sorbin and SH3 domain containing 2
  spectrin alpha, non-erythrocytic 1
  spectrin beta, non-erythrocytic 1
  spectrin beta, non-erythrocytic 2
  sperm antigen with calponin homology and coiled-coil domains 1
  sperm antigen with calponin homology and coiled-coil domains 1 like
  spermatogenesis and centriole associated 1 like
  SSU72 homolog, RNA polymerase II CTD phosphatase
  stonin 2
  supervillin
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  synaptopodin
  taperin
  TATA-box binding protein associated factor 15
  TATA-box binding protein associated factor 15
  testin LIM domain protein
  tight junction protein 1
  TNF alpha induced protein 1
  TNFAIP3 interacting protein 2
  tousled like kinase 1
  TOX high mobility group box family member 4
  TOX high mobility group box family member 4
  transmembrane protein 33
  TRIO and F-actin binding protein
  tripartite motif containing 14
  tripartite motif containing 25
  tripartite motif containing 28
  tropomodulin 1
  tropomodulin 3
  tropomyosin 1
  tropomyosin 2
  tropomyosin 3
  tropomyosin 4
  tumor necrosis factor
  tumor protein p53 binding protein 2
  twinfilin actin binding protein 1
  ubiquitin C
  ubiquitin specific peptidase 37
  ubiquitously expressed prefoldin like chaperone
  UBX domain protein 1
  UBX domain protein 2A
  UBX domain protein 2B
  unk zinc finger
  URI1 prefoldin like chaperone
  uveal autoantigen with coiled-coil domains and ankyrin repeats
  VRK serine/threonine kinase 3
  WD repeat domain 1
  WD repeat domain 5
  WD repeat domain 77
  WD repeat domain 82
  WD repeat domain 92
  WW domain binding protein 11
  WW domain containing E3 ubiquitin protein ligase 2
  YES proto-oncogene 1, Src family tyrosine kinase
  Yes1 associated transcriptional regulator
  YLP motif containing 1
  YY1 associated factor 2
  zinc finger and BTB domain containing 10
  zinc finger DHHC-type palmitoyltransferase 5
  zinc finger FYVE-type containing 9
  zinc finger protein 106
  zinc finger protein 326
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.