LGALS3BP, galectin 3 binding protein

LGALS3BP, galectin 3 binding protein

• The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

• Gene Synonyms (90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90, galectin-3-binding protein, L3 antigen, MAC2BP, Mac-2-binding protein, basement membrane autoantigen p105, lectin galactoside-binding soluble 3-binding protein, mac-2 BP, serum protein 90K, transport and golgi organization 10 homolog B, tumor-associated antigen 90K,)
• NCBI Gene ID: 3959
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q08380
  UNIPROT ID#>>A0A0S2Z3Y1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

galectin 3 binding protein interacts with:

• 5'-3' exoribonuclease 1
  5'-3' exoribonuclease 2
  5'-nucleotidase, cytosolic IIIA
  ariadne RBR E3 ubiquitin protein ligase 2
  BAG cochaperone 2
  BCL2 like 14
  branched chain keto acid dehydrogenase kinase
  CCR4-NOT transcription complex subunit 1
  CD209 molecule
  CD248 molecule
  CDK5 regulatory subunit associated protein 2
  centrosomal protein 250
  centrosomal protein 290
  centrosomal protein 55
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chromobox 1
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  CREB regulated transcription coactivator 2
  cullin 1
  cullin 2
  cullin 3
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin 9
  cullin associated and neddylation dissociated 1
  defective in cullin neddylation 1 domain containing 1
  DNA polymerase epsilon, catalytic subunit
  DnaJ heat shock protein family (Hsp40) member C13
  drosha ribonuclease III
  dynein light chain LC8-type 1
  ENAH actin regulator
  family with sequence similarity 120A
  family with sequence similarity 83 member H
  Fas associated factor family member 2
  F-box protein 45
  F-box protein 6
  F-box protein 7
  FMR1 autosomal homolog 1
  FMR1 autosomal homolog 2
  galectin 3 binding protein
  gephyrin
  glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
  glucosidase II alpha subunit
  golgi reassembly stacking protein 1
  GRB10 interacting GYF protein 2
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  HECT domain E3 ubiquitin protein ligase 4
  helicase with zinc finger 2
  histone deacetylase 5
  insulin receptor substrate 4
  integrin alpha FG-GAP repeat containing 1
  kinase suppressor of ras 1
  kinesin family member 7
  La ribonucleoprotein 7, transcriptional regulator
  leukocyte receptor cluster member 8
  MAGE family member D2
  major vault protein
  mannosyl-oligosaccharide glucosidase
  matrix Gla protein
  meiosis regulator for oocyte development
  minichromosome maintenance complex component 2
  MIS12 kinetochore complex component
  mitogen-activated protein kinase kinase kinase 7
  mitotic spindle organizing protein 1
  mitotic spindle organizing protein 1
  mitotic spindle organizing protein 2
  mitotic spindle organizing protein 2A
  mitotic spindle organizing protein 2B
  MX dynamin like GTPase 1
  MYC binding protein 2
  myoferlin
  nardilysin convertase
  NEDD1 gamma-tubulin ring complex targeting factor
  NEDD4 binding protein 2 like 2
  NEDD8 ubiquitin like modifier
  neuralized E3 ubiquitin protein ligase 4
  neurotrophic receptor tyrosine kinase 1
  neutrophil cytosolic factor 1
  NFKB repressing factor
  nidogen 1
  nitric oxide synthase 2
  NME/NM23 family member 7
  non-SMC condensin II complex subunit D3
  nucleoporin 107
  obscurin like cytoskeletal adaptor 1
  palmitoyl-protein thioesterase 1
  peptidylprolyl isomerase C
  periphilin 1
  phosphodiesterase 4D interacting protein
  phosphorylase kinase regulatory subunit beta
  pleckstrin homology domain containing A4
  potassium channel tetramerisation domain containing 5
  pre-mRNA processing factor 4
  pre-mRNA processing factor 8
  prohibitin
  prohibitin 2
  proline rich coiled-coil 2C
  protein phosphatase methylesterase 1
  pyrimidinergic receptor P2Y6
  RANBP2 like and GRIP domain containing 8
  RE1 silencing transcription factor
  required for meiotic nuclear division 5 homolog A
  ribonucleic acid export 1
  ribonucleoprotein, PTB binding 1
  ribosomal protein L23
  ribosomal protein L38
  ribosomal protein S4 X-linked
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  sel-1 suppressor of lin-12-like (C. elegans)
  selectin E
  selenoprotein F
  serine protease 21
  SHC adaptor protein 1
  sialic acid binding Ig like lectin 10
  sialic acid binding Ig like lectin 11
  sialic acid binding Ig like lectin 5
  sialic acid binding Ig like lectin 7
  sialic acid binding Ig like lectin 9
  SPRY domain containing 3
  SR-related CTD associated factor 11
  SRY-box transcription factor 2
  surfeit 4
  synaptotagmin binding cytoplasmic RNA interacting protein
  TANK binding kinase 1
  t-complex 1
  TNF receptor associated factor 3
  TNF receptor associated factor 6
  TNF receptor associated protein 1
  TNF receptor superfamily member 10a
  TNFAIP3 interacting protein 2
  trafficking protein particle complex 10
  trafficking protein particle complex 9
  transmembrane protein 161A
  transmembrane protein 63B
  tripartite motif containing 27
  tubulin alpha 1a
  tubulin alpha 1c
  tubulin beta 4B class IVb
  tubulin beta class I
  tubulin gamma 1
  tubulin gamma complex associated protein 2
  tubulin gamma complex associated protein 3
  tubulin gamma complex associated protein 4
  tubulin gamma complex associated protein 5
  tubulin gamma complex associated protein 6
  tubulin, alpha 3A
  tubulin, gamma 1
  tubulin, gamma complex associated protein 6
  twinkle mtDNA helicase
  tyrosine kinase 2
  ubiquitin associated and SH3 domain containing B
  ubiquitin conjugating enzyme E2 A
  ubiquitin specific peptidase 54
  UDP-glucose glycoprotein glucosyltransferase 1
  USO1 vesicle docking factor
  valosin containing protein interacting protein 1
  VAMP associated protein A
  vesicle associated membrane protein 5
  vir like m6A methyltransferase associated
  Wnt family member 3A
  Wnt family member 4
  Wnt family member 5A
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger CCCH-type containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.