PIBF1, progesterone immunomodulatory binding factor 1

PIBF1, progesterone immunomodulatory binding factor 1

• This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]

• Gene Synonyms (C13orf24, CEP90, JBTS33, PIBF, progesterone-induced-blocking factor 1, centrosomal protein of 90 kDa,)
• NCBI Gene ID: 10464
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WXW3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

progesterone immunomodulatory binding factor 1 interacts with:

• Abelson helper integration site 1
  angiomotin
  angiomotin like 2
  ankyrin repeat domain 23
  ankyrin repeat domain 26
  ankyrin repeat domain 28
  AT-rich interaction domain 5A
  BICD cargo adaptor 2
  BLOC-1 related complex subunit 6
  BORA aurora kinase A activator
  C2 calcium dependent domain containing 6
  caspase recruitment domain family member 10
  caspase recruitment domain family member 9
  cell division cycle 37, HSP90 cochaperone
  centriolin
  centrosomal protein 120
  centrosomal protein 120
  centrosomal protein 128
  centrosomal protein 131
  centrosomal protein 131
  centrosomal protein 135
  centrosomal protein 162
  centrosomal protein 19
  centrosomal protein 290
  centrosomal protein 43
  centrosomal protein 43
  centrosomal protein 63
  centrosomal protein 70
  centrosomal protein 72
  centrosomal protein 89
  chromobox 8
  chromosome 7 open reading frame 57
  chromosome X open reading frame 56
  cilia and flagella associated protein 53
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 13
  coiled-coil domain containing 136
  coiled-coil domain containing 138
  coiled-coil domain containing 14
  coiled-coil domain containing 77
  copine 2
  CWF19 like cell cycle control factor 2
  DISC1 scaffold protein
  discs large MAGUK scaffold protein 5
  DNA methyltransferase 1 associated protein 1
  DNA polymerase delta interacting protein 3
  DnaJ heat shock protein family (Hsp40) member B13
  EF-hand domain containing 2
  enkurin domain containing 1
  exocyst complex component 3
  FAM161 centrosomal protein A
  family with sequence similarity 50 member B
  germ cell-less 1, spermatogenesis associated
  G-patch domain and KOW motifs
  GRIP1 associated protein 1
  HAUS augmin like complex subunit 1
  homeobox and leucine zipper encoding
  immunoglobulin like and fibronectin type III domain containing 1
  katanin regulatory subunit B1 like 1
  kelch like family member 2
  kinesin family member 7
  kinesin family member 9
  KN motif and ankyrin repeat domains 2
  La ribonucleoprotein 1B
  lamin B2
  lebercilin LCA5
  leucine rich repeat and coiled-coil centrosomal protein 1
  leucine rich repeat and coiled-coil domain containing 1
  leucine zipper tumor suppressor 1
  mediator complex subunit 4
  microtubule associated protein RP/EB family member 1
  microtubule associated scaffold protein 2
  mindbomb E3 ubiquitin protein ligase 1
  mindbomb E3 ubiquitin protein ligase 1
  mitogen-activated protein kinase kinase kinase 2
  mortality factor 4 like 1
  NDC80 kinetochore complex component
  nebulette
  neural precursor cell expressed, developmentally down-regulated gene 1
  NHL repeat containing 2
  ninein
  ninein like
  nuclear RNA export factor 1
  pericentriolar material 1
  pleckstrin homology domain containing A7
  POC5 centriolar protein
  POU class 6 homeobox 2
  progesterone immunomodulatory binding factor 1
  protein kinase, cAMP dependent regulatory, type II alpha
  protein phosphatase 1 regulatory subunit 18
  protein phosphatase 1 regulatory subunit 21
  protein tyrosine phosphatase non-receptor type 21
  protein tyrosine phosphatase non-receptor type 22
  protein tyrosine phosphatase receptor type Q
  RAB11 family interacting protein 2
  radial spoke head 14 homolog
  Rho GTPase activating protein 45
  ring finger protein 151
  ring finger protein 169
  RNA binding motif protein 11
  RNA binding motif protein 48
  salvador family WW domain containing protein 1
  SAS-6 centriolar assembly protein
  serologically defined colon cancer antigen 8
  SLU7 homolog, splicing factor
  sodium channel modifier 1
  solute carrier family 25 member 41
  sorting nexin 27
  spermatogenesis associated 18
  spindle and centriole associated protein 1
  SSX family member 2 interacting protein
  synaptotagmin 17
  teashirt zinc finger homeobox 2
  teashirt zinc finger homeobox 3
  testis specific 10
  TNFAIP3 interacting protein 3
  translin associated factor X interacting protein 1
  transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
  tuftelin interacting protein 11
  unc-45 myosin chaperone A
  vesicle amine transport 1 like
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 4
  zinc finger C2HC-type containing 1C
  zinc finger C3H1-type containing
  zinc finger protein 250
  zinc finger protein 438
  zinc finger protein 620
  zinc finger protein 774

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.