GSK3A, glycogen synthase kinase 3 alpha

GSK3A, glycogen synthase kinase 3 alpha

• This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]

• Gene Synonyms (glycogen synthase kinase-3 alpha, GSK-3 alpha, serine/threonine-protein kinase GSK3A,)
• NCBI Gene ID: 2931
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0L5
  UNIPROT ID#>>P49840
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycogen synthase kinase 3 alpha interacts with:

• A-kinase anchoring protein 9
  apoptotic chromatin condensation inducer 1
  arylsulfatase G
  AT-hook DNA binding motif containing 1
  axin 1
  axin 1
  axin 2
  BCL2 associated transcription factor 1
  chaperonin containing TCP1 subunit 5
  chromosome transmission fidelity factor 18
  cullin 4B
  DEAD-box helicase 54
  DEAF1 transcription factor
  DEAF1, transcription factor
  EBNA1 binding protein 2
  eukaryotic translation initiation factor 2 subunit beta
  eukaryotic translation initiation factor 2B subunit epsilon
  family with sequence similarity 193 member B
  F-box protein 42
  FMR1 autosomal homolog 1
  FMR1 autosomal homolog 2
  FRAT regulator of WNT signaling pathway 1
  G3BP stress granule assembly factor 1
  glycogen synthase kinase 3 alpha
  GSK3B interacting protein
  heat shock protein 90 alpha family class A member 1
  heat shock transcription factor 1
  heterogeneous nuclear ribonucleoprotein K
  heterogeneous nuclear ribonucleoprotein R
  heterogeneous nuclear ribonucleoprotein U
  histone deacetylase 1
  histone deacetylase 6
  karyopherin subunit alpha 2
  KH RNA binding domain containing, signal transduction associated 1
  kinesin family member 21A
  KN motif and ankyrin repeat domains 1
  KRAB-A domain containing 1
  KRAB-A domain containing 1
  LDL receptor related protein 6
  leucine rich repeat and sterile alpha motif containing 1
  leucine zipper, putative tumor suppressor 2
  limb development membrane protein 1 like
  MCL1 apoptosis regulator, BCL2 family member
  microtubule affinity regulating kinase 3
  microtubule associated protein tau
  midasin AAA ATPase 1
  mitogen-activated protein kinase kinase kinase 11
  mitogen-activated protein kinase kinase kinase 11
  MYC proto-oncogene, bHLH transcription factor
  NBR1 autophagy cargo receptor
  NBR1, autophagy cargo receptor
  ninein
  non-POU domain containing octamer binding
  non-POU-domain-containing, octamer binding protein
  nuclear receptor subfamily 2 group C member 2
  paxillin
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  pinin, desmosome associated protein
  pleckstrin homology domain containing A4
  pleiotropic regulator 1
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  poly(ADP-ribose) polymerase family member 10
  poly(U) binding splicing factor 60
  polypyrimidine tract binding protein 1
  predicted gene 4779
  pre-mRNA processing factor 40 homolog A
  prospero homeobox 2
  proteasome 26S subunit, non-ATPase 1
  protein kinase C alpha
  protein kinase C beta
  protein kinase C delta
  protein kinase C eta
  protein kinase C gamma
  protein kinase C zeta
  protein kinase cAMP-activated catalytic subunit alpha
  protein kinase D3
  protein kinase, DNA-activated, catalytic subunit
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 1 regulatory inhibitor subunit 2
  protein phosphatase 2 catalytic subunit alpha
  protein phosphatase 3 catalytic subunit beta
  protein phosphatase 3 catalytic subunit gamma
  prune exopolyphosphatase
  regulator of calcineurin 2
  regulatory factor X7
  Rho guanine nucleotide exchange factor (GEF) 11
  Rho guanine nucleotide exchange factor 11
  ribonucleic acid export 1
  ribosomal protein L10
  ribosomal protein L11
  ribosomal protein L18
  ribosomal protein L19
  ribosomal protein L21
  ribosomal protein L32
  ribosomal protein L36a like
  ribosomal protein L4
  ribosomal protein L5
  ribosomal protein L7a
  ribosomal protein S15a
  ribosomal protein S20
  ribosomal protein S26
  ribosomal protein S27
  ribosomal protein S3A
  ribosomal protein S8
  ribosomal protein S9
  ribosomal RNA processing 1B
  RNA binding motif protein 25
  RNA binding motif protein 8A
  RNA polymerase III subunit B
  RPTOR independent companion of MTOR complex 2
  S1 RNA binding domain 1
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  serine and arginine repetitive matrix 1
  serine and arginine rich splicing factor 1
  serine and arginine rich splicing factor 3
  serine/arginine repetitive matrix 2
  serum/glucocorticoid regulated kinase 1
  serum/glucocorticoid regulated kinase family member 3
  signal transducer and activator of transcription 1
  SMAD family member 2
  SNW domain containing 1
  solute carrier family 25 member 11
  SPG21 abhydrolase domain containing, maspardin
  spindle and centriole associated protein 1
  spindle and centriole associated protein 1
  spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
  splicing factor 3a subunit 1
  splicing factor 3b subunit 3
  SRSF protein kinase 1
  SRSF protein kinase 2
  TBC1 domain family member 4
  thyroid hormone receptor associated protein 3
  TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  TRAF family member associated NFKB activator
  trafficking kinesin protein 2
  transaldolase 1
  transducin beta like 2
  trinucleotide repeat containing 18
  tripartite motif containing 25
  tripartite motif containing 28
  TSR1 ribosome maturation factor
  Tu translation elongation factor, mitochondrial
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  U2 small nuclear RNA auxiliary factor 1
  U2 small nuclear RNA auxiliary factor 2
  U2 snRNP associated SURP domain containing
  valosin containing protein
  vesicle (multivesicular body) trafficking 1
  vesicle trafficking 1
  WD repeat domain 33
  Y-box binding protein 1
  zinc finger CCCH-type containing 14
  zinc finger CCCH-type containing 6
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger, BED type containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.