GTF2E2, general transcription factor IIE subunit 2

GTF2E2, general transcription factor IIE subunit 2

• The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]

• Gene Synonyms (transcription initiation factor IIE subunit beta, TFIIE beta subunit, TFIIE-beta, general transcription factor IIE, polypeptide 2, beta 34kDa, FE, TF2E2, TFIIE-B, TTD6,)
• NCBI Gene ID: 2961
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P29084
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

general transcription factor IIE subunit 2 interacts with:

• 3-hydroxyisobutyryl-CoA hydrolase
  actin beta like 2
  activating transcription factor 7 interacting protein
  asparaginyl-tRNA synthetase 1
  bromodomain containing 7
  calcium binding protein 39
  cap methyltransferase 1
  CYFIP related Rac1 interactor B
  cysteine and histidine rich domain containing 1
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  DNA topoisomerase I
  DnaJ heat shock protein family (Hsp40) member C2
  drebrin like
  EF-hand domain family member D2
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 2A
  eukaryotic translation initiation factor 3 subunit J
  eukaryotic translation initiation factor 5B
  exocyst complex component 4
  exocyst complex component 8
  general transcription factor IIE subunit 2
  general transcription factor IIF subunit 1
  general transcription factor IIF subunit 2
  general transcription factor IIH subunit 1
  GINS complex subunit 1
  GINS complex subunit 3
  GINS complex subunit 4
  glutamine amidotransferase like class 1 domain containing 3A
  guanine monophosphate synthase
  H3 clustered histone 1
  HDGF like 2
  heat shock protein 90 alpha family class B member 1
  heterogeneous nuclear ribonucleoprotein A1
  high density lipoprotein binding protein
  high mobility group nucleosome binding domain 5
  iron-sulfur cluster assembly factor IBA57
  Jun proto-oncogene, AP-1 transcription factor subunit
  KRAS proto-oncogene, GTPase
  leucine rich repeat containing 40
  ligand of numb-protein X 1
  lysine acetyltransferase 5
  lysophospholipase 1
  MCC regulator of WNT signaling pathway
  MCTS1 re-initiation and release factor
  MDM2 proto-oncogene
  mediator of DNA damage checkpoint 1
  mesoderm development LRP chaperone
  metastasis associated 1 family member 2
  MIS18 kinetochore protein A
  MMS19 homolog, cytosolic iron-sulfur assembly component
  MNAT1 component of CDK activating kinase
  Mov10 RISC complex RNA helicase
  N-alpha-acetyltransferase 15, NatA auxiliary subunit
  nuclear RNA export factor 1
  nucleoporin 62
  Opa interacting protein 5
  phenylalanyl-tRNA synthetase subunit beta
  phosphohistidine phosphatase 1
  phosphomevalonate kinase
  polysaccharide biosynthesis domain containing 1
  programmed cell death 10
  protein interacting with PRKCA 1
  protein kinase C and casein kinase substrate in neurons 2
  protein phosphatase 1 regulatory subunit 8
  protein phosphatase methylesterase 1
  protein tyrosine phosphatase non-receptor type 11
  PYM homolog 1, exon junction complex associated factor
  regulation of nuclear pre-mRNA domain containing 1A
  ring finger protein 20
  RNA binding motif protein 12
  RNA polymerase II subunit A
  SBDS ribosome maturation factor
  SEC24 homolog D, COPII coat complex component
  serine hydroxymethyltransferase 2
  serrate, RNA effector molecule
  SIN3 transcription regulator family member A
  SLC9A3 regulator 2
  sorting nexin 5
  spliceosome associated factor 3, U4/U6 recycling protein
  splicing factor 3a subunit 1
  SPRY domain containing 4
  SPT16 homolog, facilitates chromatin remodeling subunit
  staphylococcal nuclease and tudor domain containing 1
  STE20 like kinase
  syntaxin 7
  talin 1
  TATA-box binding protein
  transforming acidic coiled-coil containing protein 3
  translocase of outer mitochondrial membrane 34
  translocated promoter region, nuclear basket protein
  tripartite motif containing 25
  tripeptidyl peptidase 2
  Ts translation elongation factor, mitochondrial
  tyrosyl-tRNA synthetase 1
  ubiquitin conjugating enzyme E2 T
  ubiquitin like domain containing CTD phosphatase 1
  ubiquitin like modifier activating enzyme 6
  ubiquitin protein ligase E3 component n-recognin 5
  UDP-glucose pyrophosphorylase 2
  VRK serine/threonine kinase 1
  WD repeat and HMG-box DNA binding protein 1
  XPA, DNA damage recognition and repair factor
  zinc finger RANBP2-type containing 2
  zinc metallopeptidase STE24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.