CSNK2B, casein kinase 2 beta

CSNK2B, casein kinase 2 beta

• This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

• Gene Synonyms (casein kinase II subunit beta, CK II beta, CSNK2B-LY6G5B-1072, CSNK2B-LY6G5B-1103, CSNK2B-LY6G5B-532, CSNK2B-LY6G5B-560, CSNK2B-LY6G5B-562, Casein kinase II beta subunit, alternative name: G5a, phosvitin, casein kinase 2, beta polypeptide, casein kinase II b subunit splicing isoform 132, casein kinase II b subunit splicing isoform 247, casein kinase II b subunit splicing isoform 318, casein kinase II b subunit splicing isoform 660, casein kinase II b subunit splicing isoform 806, chimera CSNK2B-LY6G5B splicing isoform 1072, chimera CSNK2B-LY6G5B splicing isoform 1103, chimera CSNK2B-LY6G5B splicing isoform 532, chimera CSNK2B-LY6G5B splicing isoform 560, chimera CSNK2B-LY6G5B splicing isoform 562, phosvitin, protein G5a, CK2B, CK2N, CSK2B, Ckb1, Ckb2, G5A, POBINDS,)
• NCBI Gene ID: 1460
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A1U9X7J2
  UNIPROT ID#>>N0E4C7
  UNIPROT ID#>>P67870
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

casein kinase 2 beta interacts with:

• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
  AAR2 splicing factor
  abhydrolase domain containing 4, N-acyl phospholipase B
  actin like 6B
  actin related protein 1B
  actin related protein 5
  activator of transcription and developmental regulator AUTS2
  ankyrin repeat domain 28
  ataxin 3
  ATPase, Cu++ transporting, alpha polypeptide
  autophagy related 101
  autophagy related 16 like 1
  BAG cochaperone 6
  basic helix-loop-helix family member e41
  beta-transducin repeat containing E3 ubiquitin protein ligase
  BRCA2 and CDKN1A interacting protein
  bromodomain containing 2
  BTG3 associated nuclear protein
  capicua transcriptional repressor
  casein kinase 2 beta
  catenin beta 1
  CD163 molecule
  cell division cycle 37, HSP90 cochaperone
  centrosomal protein 170
  chromobox 2
  chromobox 4
  chromobox 7
  chromobox 8
  chromosome 6 open reading frame 136
  clock circadian regulator
  CLOCK interacting pacemaker
  coiled-coil domain containing 106
  coiled-coil domain containing 115
  coiled-coil domain containing 187
  coilin
  COP9 signalosome subunit 3
  COP9 signalosome subunit 7A
  copine 7
  CTD phosphatase subunit 1
  cullin 7
  cyclin dependent kinase 11A
  cyclin dependent kinase 16
  cyclin dependent kinase 20
  cystatin SN
  DALR anticodon binding domain containing 3
  DDB1 and CUL4 associated factor 7
  DENN domain containing 5A
  dihydrolipoamide dehydrogenase
  dishevelled binding antagonist of beta catenin 1
  dishevelled segment polarity protein 2
  DNA methyltransferase 1
  DNA topoisomerase II alpha
  DNA topoisomerase II beta
  double PHD fingers 3
  dynein cytoplasmic 1 heavy chain 1
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  enhancer of zeste 2 polycomb repressive complex 2 subunit
  epidermal growth factor receptor pathway substrate 8
  erythrocyte membrane protein band 4.1 like 3
  estrogen receptor 1
  estrogen receptor 2
  eukaryotic translation initiation factor 2 subunit beta
  eukaryotic translation initiation factor 3 subunit F
  eukaryotic translation initiation factor 3 subunit H
  eukaryotic translation initiation factor 5
  eukaryotic translation initiation factor 6
  exportin 1
  Fas associated factor 1
  F-box and leucine rich repeat protein 15
  F-box and leucine rich repeat protein 5
  ferritin heavy chain 1
  FGF1 intracellular binding protein
  fibrinogen beta chain
  fibroblast growth factor 1
  fibroblast growth factor 2
  fibronectin 1
  FKBP prolyl isomerase 3
  G protein subunit beta 5
  GADD45G interacting protein 1
  galactosidase beta 1
  GLIS family zinc finger 2
  glycogen synthase kinase 3 beta
  GTP cyclohydrolase 1
  guanidinoacetate N-methyltransferase
  guanylate binding protein 2
  heat shock protein 90 alpha family class A member 1
  hes related family bHLH transcription factor with YRPW motif 1
  heterogeneous nuclear ribonucleoprotein A2/B1
  HEXIM P-TEFb complex subunit 1
  HEXIM P-TEFb complex subunit 2
  hexosaminidase subunit beta
  HIRA interacting protein 3
  histone deacetylase 1
  homeobox B5
  homeobox B6
  HtrA serine peptidase 1
  huntingtin interacting protein K
  HUS1 checkpoint clamp component
  hydroxysteroid 17-beta dehydrogenase 10
  immediate early response 3 interacting protein 1
  inhibitor of nuclear factor kappa B kinase subunit beta
  INO80 complex subunit B
  insulin receptor substrate 1
  integrator complex subunit 11
  integrin alpha FG-GAP repeat containing 1
  integrin subunit alpha 4
  interferon gamma inducible protein 16
  interferon regulatory factor 1
  intersectin 1
  IQ motif containing GTPase activating protein 1
  junctophilin 4
  kinase suppressor of ras 1
  kinesin family member 2C
  KRAS proto-oncogene, GTPase
  La ribonucleoprotein 7, transcriptional regulator
  LCK proto-oncogene, Src family tyrosine kinase
  LDL receptor related protein 5 like
  leptin receptor
  LIM domain only 4
  LYN proto-oncogene, Src family tyrosine kinase
  lysine demethylase 5C
  lysine demethylase 6B
  MAGE family member B2
  MAPK activated protein kinase 2
  MAX dimerization protein MLX
  MDM2 proto-oncogene
  MDS1 and EVI1 complex locus
  membrane metalloendopeptidase
  membrane palmitoylated protein 2
  methyl-CpG binding domain 4, DNA glycosylase
  methylphosphate capping enzyme
  microspherule protein 1
  microtubule associated serine/threonine kinase 3
  monooxygenase DBH like 1
  MYC proto-oncogene, bHLH transcription factor
  neuroguidin
  neuronal PAS domain protein 2
  neurotrophic receptor tyrosine kinase 1
  neutrophil cytosolic factor 1
  NFKB activating protein
  NFKB inhibitor alpha
  NKAP domain containing 1
  N-myristoyltransferase 2
  notch receptor 3
  N-terminal glutamine amidase 1
  nuclear receptor binding protein 1
  nuclear receptor subfamily 2 group C member 2
  nuclear respiratory factor 1
  nuclear RNA export factor 1
  nucleolar and coiled-body phosphoprotein 1
  nucleophosmin 1
  nucleosome assembly protein 1 like 1
  obscurin like cytoskeletal adaptor 1
  occludin
  O-GlcNAcase
  O-linked N-acetylglucosamine (GlcNAc) transferase
  ornithine decarboxylase 1
  PAX interacting protein 1
  PDS5 cohesin associated factor A
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  peptidylprolyl isomerase D
  period circadian regulator 1
  period circadian regulator 2
  PHD and ring finger domains 1
  PHD finger protein 11
  phosphatidylinositol transfer protein alpha
  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
  phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
  PICALM interacting mitotic regulator
  PIH1 domain containing 1
  pituitary tumor-transforming 2
  pleckstrin homology domain containing A4
  plexin A3
  PML nuclear body scaffold
  polycomb group ring finger 3
  polycomb group ring finger 5
  polycomb group ring finger 6
  polyhomeotic homolog 2
  PR/SET domain 16
  pre-mRNA processing factor 38A
  prion protein
  protection of telomeres 1
  protein C, inactivator of coagulation factors Va and VIIIa
  protein kinase AMP-activated non-catalytic subunit beta 2
  protein kinase C zeta
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 2 catalytic subunit alpha
  protein phosphatase 2 regulatory subunit B'delta
  protein phosphatase 2 regulatory subunit B'epsilon
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase 2 scaffold subunit Abeta
  protein phosphatase 3 catalytic subunit gamma
  protein tyrosine phosphatase receptor type K
  PTTG1 regulator of sister chromatid separation, securin
  pyridine nucleotide-disulphide oxidoreductase domain 2
  pyrin and HIN domain family member 1
  RAD1 checkpoint DNA exonuclease
  RAD18 E3 ubiquitin protein ligase
  RAD51 recombinase
  RAD9 checkpoint clamp component A
  RAR related orphan receptor B
  Ras association domain family member 10
  Ras association domain family member 9
  RecQ like helicase 4
  replication factor C subunit 1
  replication protein A1
  retinoid X receptor alpha
  ribosomal protein L13
  ribosomal protein L41
  ribosomal protein L5
  ribosomal protein S6 kinase A1
  ribosomal protein S6 kinase A2
  ribosomal protein S6 kinase A5
  ribosomal protein S6 kinase B1
  ribosomal protein S6 kinase B2
  ring finger protein 1
  ring finger protein 11
  ring finger protein 126
  ring finger protein 2
  ring finger protein 7
  RING1 and YY1 binding protein
  RNA binding motif protein 39
  RNA binding protein with serine rich domain 1
  RNA polymerase II associated protein 1
  RNA polymerase II, I and III subunit E
  RRAD, Ras related glycolysis inhibitor and calcium channel regulator
  SAP domain containing ribonucleoprotein
  SEC11 homolog A, signal peptidase complex subunit
  selenoprotein I
  serine and arginine repetitive matrix 1
  serine hydroxymethyltransferase 1
  serine hydroxymethyltransferase 2
  serine/threonine kinase 16
  SH3 and multiple ankyrin repeat domains 3
  signal transducer and activator of transcription 5A
  sirtuin 1
  small nuclear ribonucleoprotein U1 subunit 70
  small RNA binding exonuclease protection factor La
  small ubiquitin like modifier 2
  sorting nexin 2
  spectrin repeat containing nuclear envelope family member 4
  splA/ryanodine receptor domain and SOCS box containing 3
  SPOUT domain containing methyltransferase 1
  SPT16 homolog, facilitates chromatin remodeling subunit
  SPT5 homolog, DSIF elongation factor subunit
  staufen double-stranded RNA binding protein 1
  structure specific recognition protein 1
  succinate dehydrogenase complex flavoprotein subunit A
  SUMO interacting motifs containing 1
  SUZ12 polycomb repressive complex 2 subunit
  synuclein alpha interacting protein
  T cell leukemia homeobox 3
  TATA-box binding protein associated factor, RNA polymerase I subunit D
  Tctex1 domain containing 2
  telomeric repeat binding factor 1
  telomeric repeat binding factor 2
  teneurin transmembrane protein 1
  TLE family member 1, transcriptional corepressor
  TNF alpha induced protein 1
  TNFAIP3 interacting protein 2
  transcription elongation factor A like 7
  transcription factor 7 like 2
  transcription factor AP-2 alpha
  transcription factor AP-2 delta
  treacle ribosome biogenesis factor 1
  tribbles pseudokinase 3
  tripartite motif containing 54
  tRNA splicing endonuclease subunit 54
  tubulin beta 2B class IIb
  tumor protein p53
  tumor protein p53 binding protein 2
  tumor protein p63
  twinfilin actin binding protein 1
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 43
  unk zinc finger
  UPF1 RNA helicase and ATPase
  USO1 vesicle transport factor
  UTP14A small subunit processome component
  valosin containing protein
  vascular cell adhesion molecule 1
  visual system homeobox 1
  voltage dependent anion channel 1
  VRK serine/threonine kinase 3
  WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
  WD repeat domain 1
  WD repeat domain 12
  WD repeat domain 18
  WD repeat domain 48
  WEE1 G2 checkpoint kinase
  WW domain containing oxidoreductase
  YY1 associated factor 2
  zinc finger and SCAN domain containing 5A
  zinc finger HIT-type containing 1
  zinc finger protein 19
  zinc finger protein 410
  zinc finger protein 44
  zinc finger protein 71
  zinc finger protein 784

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.